CSTF3

  • Official Full Name

    cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa

  • Overview

    The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3 end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

  • Synonyms

    CSTF3;cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa;cleavage stimulation factor, 3 pre RNA, subunit 3, 77kD;cleavage stimulation factor subunit 3;CstF 77;CF-1 77 kDa subunit;CSTF 77 kDa subunit;cleavage stimulation factor 77 kDa subunit

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CSTF3-11652H Recombinant Human CSTF3, GST-tagged E.coli Human GST 1-103a.a.
CSTF3-1072R Recombinant Rhesus monkey CSTF3 Protein, His-tagged Mammalian Cell Rhesus macaque His
CSTF3-12288Z Recombinant Zebrafish CSTF3 Mammalian Cell Zebrafish His
CSTF3-1940C Recombinant Chicken CSTF3 Mammalian Cell Chicken His
CSTF3-2044H Recombinant Human CSTF3 Protein, GST-tagged Wheat Germ Human GST
CSTF3-7222HCL Recombinant Human CSTF3 293 Cell Lysate HEK293 Human Non
CSTF3-2253HF Recombinant Full Length Human CSTF3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 103 amino acids
Cstf3-2350M Recombinant Mouse Cstf3 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
CSTF3-897R Recombinant Rhesus Macaque CSTF3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
CSTF3-897R-B Recombinant Rhesus Macaque CSTF3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    CSTF3 involved in several pathways and played different roles in them. We selected most pathways CSTF3 participated on our site, such as Cleavage of Growing Transcript in the Termination Region,Gene Expression,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSTF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression ZNF567,USP9X,ZIM3,PUS7,GTF3C3,ZNF621,HNRNPA2B1,ZNF473,ZNF43,ZNF776
    Processing of Capped Intron-Containing Pre-mRNA SNRNP25,SUGP1,CD2BP2,BCAS2,HNRNPL2,SF3A3,HNRNPH1L,METTL14,ZMAT5,SLBP
    RNA Polymerase II Transcription Termination NUDT21,PAPOLA,LSM10,U2AF2,CSTF2,ZNF473,RNPS1,ZFP473,SRSF11,CLP1
    RNA Polymerase II Transcription NELFE,PAPOLA,GM3258,RNPS1,LSM10,SUPT16H,CSTF1,ZNF473,LSM11,SRSF11
    Processing of Intronless Pre-mRNAs PAPOLA,CLP1,CSTF1,CSTF2,NUDT21
    Cleavage of Growing Transcript in the Termination Region NUDT21,U2AF2,SRSF11,ZFP473,ZNF473,LSM10,CSTF1,SLBP,LSM11,CLP1
    mRNA 3-end processing CLP1,SRSF11,NUDT21,SFRS3A,CSTF2
    Processing of Capped Intronless Pre-mRNA LSM11,CSTF2,NUDT21,LSM10,CLP1,ZFP473,PAPOLA,SLBP,CSTF1,ZNF473

    Protein Function

    CSTF3 has several biochemical functions, for example, RNA binding,mRNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSTF3 itself. We selected most functions CSTF3 had, and list some proteins which have the same functions with CSTF3. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding HIST1H4I,DIMT1,TCP1,VCP,KIAA1429,GLRX3,TES,EIF3I,TNPO1,FNDC3A
    RNA binding SCAF8,RBMS3,DAZAP1,SMARCE1,CPSF5,CNOT4B,RDBP,RBM8A,PAIP1,DPPA5A
    protein binding POU2F3,CYP2S1,DACT2,CASP1,ZNF295,UPF3A,DYM,FAM86A,BIRC3,MED28
    mRNA binding NXF3,LUC7L3,DHFRL1,PAIP2,DPPA5A,AGO2,PURB,DHFR,RC3H2,MRPL13

    Interacting Protein

    CSTF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSTF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSTF3.

    CDK4;VHL;IKBKE;emrR;15-deoxy-delta(12,14;ssrna_ug;NPM1;SNW1;RNPS1;FIP1L1;Myh9

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