CST8
-
Official Full Name
cystatin 8 (cystatin-related epididymal specific) -
Overview
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing identified in mouse is suggested in human based on EST evidence but the full-length nature of putative variants has not been determined. -
Synonyms
CST8;cystatin 8 (cystatin-related epididymal specific);cystatin-8;CRES;CST 8;CST8_HUMAN;cystatin 8 (cystatin related epididymal specific);Cystatin 8;Cystatin related epididymal specific;Cystatin related epididymal specific protein;Cystatin related epididymal spermatogenic protein;Cystatin related protein epididymis specific;Cystatin-related epididymal spermatogenic protein;cystatin-related epididymal-specific
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CST8-2033H | Recombinant Human CST8 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| CST8-667H | Recombinant Human CST8 Protein, Fc-tagged | HEK293 | Human | Fc | 1-142 a.a. |
|
| CST8-76H | Recombinant Human CST8, His-tagged | HEK293 | Human | His | 22-142 a.a. |
|
| CST8-7226HCL | Recombinant Human CST8 293 Cell Lysate | HEK293 | Human | Non |
|
|
| CST8-2241HF | Recombinant Full Length Human CST8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 90 amino acids |
|
| Cst8-5417M | Recombinant Mouse Cst8 Protein (Met1-Pro98), N-His tagged | E.coli | Mouse | His | Met1-Pro98 |
|
Involved Pathway
CST8 involved in several pathways and played different roles in them. We selected most pathways CST8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CST8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CST8 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CST8 itself. We selected most functions CST8 had, and list some proteins which have the same functions with CST8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity | BIRC5B,SERPINB13,CST7,CST3,LCN1,CST6,CST4,CST14B.1,CARD18,CST5 |
Interacting Protein
CST8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CST8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CST8.
Resources
Related Services
Related Products
References
