CRTC1
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Official Full Name
CREB regulated transcription coactivator 1 -
Overview
Glucose homeostasis is regulated by hormones and cellular energy status. Elevations of blood glucose during feeding stimulate insulin release from pancreatic beta-cells through a glucose sensing pathway. Feeding also stimulates release of gut hormones suc -
Synonyms
CRTC1;CREB regulated transcription coactivator 1;MECT1, mucoepidermoid carcinoma translocated 1;CREB-regulated transcription coactivator 1;FLJ14027;KIAA0616;TORC1;TORC-1;transducer of CREB protein 1;mucoepidermoid carcinoma translocated 1;mucoe
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His&T7
- His
- GST
- Non
- Avi&His&Fc
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CRTC1 involved in several pathways and played different roles in them. We selected most pathways CRTC1 participated on our site, such as HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRTC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HTLV-I infection | MSX1,TRP53,WNT7A,CANX,VDAC2,RELA,EP300,PCNA,HLA-DQA1,RAN |
Protein Function
CRTC1 has several biochemical functions, for example, cAMP response element binding protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRTC1 itself. We selected most functions CRTC1 had, and list some proteins which have the same functions with CRTC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CDK5RAP3,GOLGA8G,SNX12,KLRD1,BSG,OAZ2,ZNF394,MEMO1,BACH1,C9orf24 |
| cAMP response element binding protein binding | DDIT3,CRTC1A,ATF2,CREB3,KCNA3,CRTC3,CRTC2,DAPK3,CREM |
Interacting Protein
CRTC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRTC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRTC1.
bzlf1_ebvb9;CREB1;MEIS1;YWHAH
Resources
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References
- Ho, AK; Price, DM; et al. Acetylation of histone H3 and adrenergic-regulated gene transcription in rat pinealocytes. ENDOCRINOLOGY 148:4592-4600(2007).
- Shindo, S; Numazawa, S; et al. A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction. BIOCHEMICAL JOURNAL 401:735-741(2007).
