COX7C
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Official Full Name
COX7C cytochrome c oxidase subunit VIIc [ Homo sapiens ] -
Overview
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. -
Synonyms
COX7C;COX7C_HUMAN;Cytochrome c oxidase polypeptide VIIc;Cytochrome c oxidase subunit 7C;mitochondrial;cytochrome-c oxidase chain VIIc
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
COX7C involved in several pathways and played different roles in them. We selected most pathways COX7C participated on our site, such as Alzheimers disease,Cardiac muscle contraction,Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX7C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cardiac muscle contraction | MYH15,CACNA1C,COX5AA,TMEM8C,TPMA,ATP1A1B,COX7B2,UQCRC2,ATP2A2,COX8C |
| Metabolism | CES1,PDPR,DTYMK,GGT6,DSEL,KCNB1,NDUFAF5,CPNE3,TPH2,CYP27B1 |
| Electron Transport Chain | UCP2,UCP3,COX6A2,COX6B1,COX4I1,SLC25A27,COX6A1,NDUFS7,NDUFC2-KCTD14,ATP5L |
| Metabolic pathways | ALAD,LIPT2,ACSM5,PIPOX,NADSYN1,FBP1B,ASNS,ACOX3,PIGQ,CYP2S1 |
| Generic Transcription Pathway | ZNF584,NR0B2A,HBXIP,ZNF454,TRIM33,ZNF606,ZNF75A,ZNF436,ZNF764,TXN |
| Gene Expression | ZNF202,GLS2B,Txn1,POP4,BRF1B,NR2F6,DARS,MED13B,RBB4L,AARS |
| Alzheimers disease | CALM4,PPP3CB,NDUFA4L2,NDUFV3,NDUFB5,ADAM10,IL1B,COX6B1,PLCB3,ATP2A3 |
| Huntingtons disease | HAP1,NDUFA8,ATP5G3,RCOR1,POLR2J2,ATP5O,BBC3,GPX1,DCTN4,NDUFB6 |
Protein Function
COX7C has several biochemical functions, for example, cytochrome-c oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COX7C itself. We selected most functions COX7C had, and list some proteins which have the same functions with COX7C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytochrome-c oxidase activity | COX6A2,COX5B,COX6B1,COX11,COX7A2A,COX15,SURF1,COX7A2L,COX5AA,COX6C |
Interacting Protein
COX7C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX7C here. Most of them are supplied by our site. Hope this information will be useful for your research of COX7C.
MT-CO2;CLPP
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