COPB1
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Official Full Name
coatomer protein complex, subunit beta 1 -
Overview
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer;complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated;guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and;lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. -
Synonyms
COPB1;coatomer protein complex, subunit beta 1;coatomer protein complex, subunit beta , COPB;coatomer subunit beta;Beta-coat protein;betacop;Coatomer beta subunit;Coatomer protein complex subunit beta 1;Coatomer protein complex subunit beta;COPB;DKFZp761K102;FLJ10341;beta-cop;beta coat protein;OTTHUMP00000231098;OTTHUMP00000231099
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
- His&GST
Involved Pathway
COPB1 involved in several pathways and played different roles in them. We selected most pathways COPB1 participated on our site, such as COPI Mediated Transport,Golgi to ER Retrograde Transport,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with COPB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vesicle-mediated transport | COPE,NECAP1,BLOC1S3,GJD3,HSPH1,TPD52,TGOLN2,PPP6C,SNX9,CNO |
| Membrane Trafficking | GJB3,LMAN2,GJB7,RALAB,SEC22A,MYO1C,GJB4,CNO,TRAPPC6B,EXOC1 |
| COPI Mediated Transport | COPE,ARCN1,ARCN1B,COPB2,COPG,ARCN1A,TERFA,ARF1,COPZ1 |
| Golgi to ER Retrograde Transport | ARCN1,TERFA,COPB2,COPZ1,COPE,ARCN1A,COPG,ARCN1B |
Protein Function
COPB1 has several biochemical functions, for example, protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COPB1 itself. We selected most functions COPB1 had, and list some proteins which have the same functions with COPB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PCBP2,EED,MTMR7,APEX1,LNPEP,SIT1,ASF1A,ZNF177,DOK6,CSNK2B |
| structural molecule activity | CLDN17,KRT86,TUBA1A,MAP2,COPG2,KRT72-PS,KRT38,MTAP7D2,COL18A1,CYLC1 |
Interacting Protein
COPB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COPB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COPB1.
Copa;SUN2;NUDCD1;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;TNFRSF1B;GBF1;TRIM37;HLA-DPB1;XRCC6;ID1;HTT
Resources
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References
- Han, XL; Yang, HW; et al. Investigation of four candidate genes (IGF2, JHDM1A, COPB1 and TEF1) for growth rate and backfat thickness traits on SSC2q in Large White pigs. MOLECULAR BIOLOGY REPORTS 41:309-315(2014).
- Qiu, HF; Xu, XW; et al. Investigation of LDHA and COPB1 as candidate genes for muscle development in the MYOD1 region of pig chromosome 2. MOLECULAR BIOLOGY REPORTS 37:629-636(2010).
