COL11A1
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Official Full Name
collagen, type XI, alpha 1 -
Overview
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. -
Synonyms
COL11A1;collagen, type XI, alpha 1;COLL6;collagen alpha-1(XI) chain;CO11A1;collagen XI;alpha 1 polypeptide;STL2;Collagen alpha 1;collagen XI alpha 1;collagen XI, alpha 1 polypeptide;STL3;XI chain precursor;OTTHUMP00000012567;OTTHUMP00000218241;collagen XI, alpha-1 polypeptide
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COL11A1-15H | Recombinant Human COL11A1 protein, His-tagged | E.coli | Human | His | Asp1564~Gly1806 | |
| COL11A1-1516R | Recombinant Rat COL11A1 Protein | Mammalian Cells | Rat | His |
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| COL11A1-1173R | Recombinant Rat COL11A1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| COL11A1-1173R-B | Recombinant Rat COL11A1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| COL11A1-2792H | Recombinant Human COL11A1 Protein, His-tagged, OVA Conjugated | Protein Conjugation | Human | His | Gln512-Arg528 |
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| COL11A1-4253H | Recombinant Human COL11A1 protein, His-GST-tagged | E.coli | Human | His&GST | 532-699aa |
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Involved Pathway
COL11A1 involved in several pathways and played different roles in them. We selected most pathways COL11A1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COL11A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
COL11A1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by COL11A1 itself. We selected most functions COL11A1 had, and list some proteins which have the same functions with COL11A1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
COL11A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL11A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL11A1.
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References
- Fuentes-Martinez, N; Garcia-Pravia, C; et al. Overexpression of proCOL11A1 as a stromal marker of breast cancer. HISTOLOGY AND HISTOPATHOLOGY 30:87-93(2015).
- Galvan, JA; Garcia-Martinez, J; et al. Validation of COL11A1/procollagen 11A1 expression in TGF-beta 1-activated immortalised human mesenchymal cells and in stromal cells of human colon adenocarcinoma. BMC CANCER 14:-(2014).
