CLIP2
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Official Full Name
CAP-GLY domain containing linker protein 2 -
Overview
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] -
Synonyms
CLIP2;CAP-GLY domain containing linker protein 2;CLIP;CYLN2;WSCR3;WSCR4;WBSCR3;WBSCR4;CLIP-115;CAP-Gly domain-containing linker protein 2;cytoplasmic linker 2;cytoplasmic linker protein 2;cytoplasmic linker protein 115;Williams-Beuren syndrome chromosome region 3;Williams-Beuren syndrome chromosome region 4;williams-Beuren syndrome chromosomal region 3 protein;williams-Beuren syndrome chromosomal region 4 protein
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CLIP2 involved in several pathways and played different roles in them. We selected most pathways CLIP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CLIP2 has several biochemical functions, for example, microtubule plus-end binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIP2 itself. We selected most functions CLIP2 had, and list some proteins which have the same functions with CLIP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule plus-end binding | CLIP1,CLASP1A,STIM1,MAPRE1,APC,KIF2C,DST,CLASP1,KIF18A |
Interacting Protein
CLIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIP2.
MAX;sbcC;Dnaaf5;MAPRE1;Sidt2;KLC4;Timeless
Resources
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References
- Ripoll, VM; Lambrianides, A; et al. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. BLOOD 124:3808-3816(2014).
