CLEC2B
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Official Full Name
C-type lectin domain family 2, member B -
Overview
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. -
Synonyms
CLEC2B;C-type lectin domain family 2, member B;C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 2 (activation induced) , CLECSF2;C-type lectin domain family 2 member B;AICL;HP10085;Activation induced C type lectin;C type lectin domain family 2 member B;C type lectin superfamily member 2;CLEC2;CLECSF2;IFN alpha2b inducing related protein 1;IFNRG1;activation-induced C-type lectin;C-type lectin superfamily member 2;IFN-alpha2b-inducing related protein 1;IFN-alpha-2b-inducing-related protein 1;C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced)
Recombinant Proteins
- Human
- Rhesus macaque
- Insect Cell
- Wheat Germ
- HEK293
- E.coli
- Mammalian Cell
- In Vitro Cell Free System
- His&Fc
- GST
- Fc
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLEC2B-001H | Recombinant Human CLEC2B Protein, hIgG-His-tagged | Insect Cell | Human | His&Fc | 26-149 a.a. | |
| CLEC2B-1462H | Recombinant Human CLEC2B Protein, GST-tagged | Wheat Germ | Human | GST |
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| CLEC2B-454H | Recombinant Human CLEC2B Protein, Fc-tagged | HEK293 | Human | Fc | 26-149 a.a. |
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| CLEC2B-7120H | Recombinant Human CLEC2B, His-tagged | E.coli | Human | His | 26-149aa |
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| CLEC2B-905R | Recombinant Rhesus monkey CLEC2B Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CLEC2B-7452HCL | Recombinant Human CLEC2B 293 Cell Lysate | HEK293 | Human | Non |
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| CLEC2B-2132HF | Recombinant Full Length Human CLEC2B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 149 amino acids |
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| CLEC2B-730R | Recombinant Rhesus Macaque CLEC2B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CLEC2B-730R-B | Recombinant Rhesus Macaque CLEC2B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
CLEC2B involved in several pathways and played different roles in them. We selected most pathways CLEC2B participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | CD300LH,CRTAM,TREML2,LILRA3,SIGLEC10,CXADR,AMICA1,CD96,LAIR1,SLAMF6 |
| Immune System | CD200R3,SLAMF6,GBP5,KIFAP3,NLRP3,FBXO3,POLR3G,MGC174857,DTX3L,CFHL1 |
| Adaptive Immune System | TRIM9,SIGLEC10,BLK,RNF25,CLTA,CTSL1,DYNC1LI2,TREML1,LILRB1,CREB1 |
Protein Function
CLEC2B has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC2B itself. We selected most functions CLEC2B had, and list some proteins which have the same functions with CLEC2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | LMAN2,SIGLEC11,NOMO2,GALNTL4,LGALSLB,KLRC2,GANAB,GALM,KLRA8,CLEC4A2 |
Interacting Protein
CLEC2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC2B here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC2B.
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