CLDN23
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Official Full Name
claudin 23 -
Overview
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. -
Synonyms
CLDN23;claudin 23;claudin-23;CLDNL;2310014B08Rik;Claudin23;CLDN 23;hCG1646163
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLDN23-11294H | Recombinant Human CLDN23, GST-tagged | E.coli | Human | GST | C-term-109a.a. | |
| CLDN23-3627H | Recombinant Human CLDN23 protein, His-tagged | E.coli | Human | His | 184-292 aa | |
| CLDN23-7464HCL | Recombinant Human CLDN23 293 Cell Lysate | HEK293 | Human | Non |
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| RFL19091HF | Recombinant Full Length Human Claudin-23(Cldn23) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-292) |
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| RFL2812MF | Recombinant Full Length Mouse Claudin-23(Cldn23) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-296) |
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Involved Pathway
CLDN23 involved in several pathways and played different roles in them. We selected most pathways CLDN23 participated on our site, such as Cell adhesion molecules (CAMs),Cell junction organization,Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell-Cell communication | SIRPB1,DSCAMA,KIRRELA,CDH11,KIRREL,FERMT2,KIRREL3,F11R.2,ANG,CDH12 |
| Leukocyte transendothelial migration | MAPK12,MLLT4,PIK3R5,CLDN22,VASP,ITGAL,CLDN18,RASSF5,PTK2B,PIK3CB |
| Tight junction interactions | CLDN4,CLDN7,CLDN20,CLDN3,CLDN16,INADL |
| Hepatitis C | NFKBIA,EIF2AK3,PIK3CA,IRF9,CLDN15,IFNAR1,OAS1A,CLDN14,GSK3B,IFNA17 |
| Cell junction organization | CDH10,CDH18,CDH8,CDH10A,CLDN16,CDH11,CTNND1,CDH3,CLDN3,TESK1 |
| Cell-cell junction organization | CDH11,CDH18A,CDH10,CLDN4,CDH9,JUPA,CDH8,CLDN16,CDH6,CADM2B |
| Tight junction | INADL,SPTAN1,RRAS,CLDN10A,PARD3,PTENA,KRAS,MYH7B,CLDNC,HCLS1 |
| Cell adhesion molecules (CAMs) | NFASCA,CD6,CLDNA,BF1,CD86,NRXN3A,HLA-DRB3,MHC2A,MHC1UXA2,MHC1UEA |
Protein Function
CLDN23 has several biochemical functions, for example, identical protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN23 itself. We selected most functions CLDN23 had, and list some proteins which have the same functions with CLDN23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | NOXO1,LRRK2,ALK,MCPH1,SNX1,GDF5,RUVBL2,NUP153,EED,CAD |
| structural molecule activity | CLDN16,KRT80,CLDN10B,IFFO2,SPRR2D,ASPH,EVPLA,CLDNE,SEPT7,NEFMA |
Interacting Protein
CLDN23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN23 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN23.
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