CKS2
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Official Full Name
CDC28 protein kinase regulatory subunit 2 -
Overview
CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. -
Synonyms
CKS2;CDC28 protein kinase regulatory subunit 2;CKSHS2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rhesus macaque
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- T7
- His
- Non
- His&Fc&Avi
- Myc&DDK
- His&Myc
Involved Pathway
CKS2 involved in several pathways and played different roles in them. We selected most pathways CKS2 participated on our site, such as Pathways in cancer,Small cell lung cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Small cell lung cancer | NFKB1,TRAF6,PIK3R5,XIAP,ITGB1,PTGS2,CCNE2,SKP2,TRAF4,ITGA2B |
| Pathways in cancer | FZD3,WNT4,LPAR2,MTOR,PLCB1,FZD10,FGF4,CTNNA3,ITGA2,NOS2 |
Protein Function
CKS2 has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CKS2 itself. We selected most functions CKS2 had, and list some proteins which have the same functions with CKS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cyclin-dependent protein serine/threonine kinase regulator activity | CCNL1,PSTPIP2,CCNK,CCNT1,CCNT2,CCNT2B,FAM58A,CCNY,CCNL1B,CCNL1A |
Interacting Protein
CKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CKS2.
CDK1;CDK2;Cdk1;VTN;GRB2;EEF1A1;UNC119;BLZF1;TSC22D4;CCNB1
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