CHIC2
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Official Full Name
cysteine-rich hydrophobic domain 2 -
Overview
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. -
Synonyms
CHIC2;cysteine-rich hydrophobic domain 2;cysteine-rich hydrophobic domain 2 protein;BTL;BRX-like translocated in leukemia;cystein-rich hydrophobic domain 2;MGC21173
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CHIC2 involved in several pathways and played different roles in them. We selected most pathways CHIC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHIC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CHIC2 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHIC2 itself. We selected most functions CHIC2 had, and list some proteins which have the same functions with CHIC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | HOXC12,CRYGM2D12,TAS2R109,PRRT4,FIP1L1B,CBLN8,XKR7,ERICH3,GM12695,CCDC127A |
| protein binding | EFCAB4A,BEND3,BEND7,KRTAP19-5,SAP30,TRPC4AP,CNOT8,NAT10,GP1BA,GPANK1 |
Interacting Protein
CHIC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHIC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHIC2.
PLEKHF2;MEOX2;TCF4;KRTAP5-9;KRTAP10-7
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References
- Lamarre, C; Deslauriers, N; et al. Expression cloning of the Candida albicans CSA1 gene encoding a mycelial surface antigen by sorting of Saccharomyces cerevisiae transformants with monoclonal antibody-coated magnetic beads. MOLECULAR MICROBIOLOGY 35:444-453(2000).
- Qing, J; Wei, D; et al. Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines. ONCOGENE 18:335-342(1999).
