CFHR1
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Official Full Name
complement factor H-related 1 -
Overview
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. -
Synonyms
CFHR1;complement factor H-related 1;CFHL1, CFHL1P, CFHR1P, complement factor H related 1 pseudogene , H factor (complement) like 1 , H factor (complement) like 2 , HFL1, HFL2;complement factor H-related protein 1;CFHL;FHR1;H36 1;H36 2;CFHL1;CFHL1P;CFHR1P;Complement factor H related 1 pseudogene;Complement factor H related protein 1 precursor;FHR 1;FHR-1;FHR1_HUMAN;H factor (complement) like 1;H factor (complement) like 2;H factor like protein 1;H factor-like protein 1;H-factor-like 1;H36;HFL1;HFL2;MGC104329;H factor (complement)-like 1;H factor (complement)-like 2;complement factor H-related 1 pseudogene;H36-1;H36-2
Recombinant Proteins
- Human
- Zebrafish
- Wheat Germ
- Mammalian Cell
- HEK293
- Human Cell
- Mammalian cells
- E. coli
- E.coli
- GST
- His
- Non
- N-His-GST&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CFHR1-27138TH | Recombinant Human CFHR1 protein, GST-tagged | Wheat Germ | Human | GST | 19-330 a.a. | |
| CFHL1-3595Z | Recombinant Zebrafish CFHL1 | Mammalian Cell | Zebrafish | His |
|
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| CFHR1-268H | Recombinant Human CFHR1, His-tagged | HEK293 | Human | His | Glu19-Arg330 |
|
| CFHR1-269H | Recombinant Human CFHR1, His-tagged | Mammalian Cell | Human | Non | 19-330 a.a. |
|
| CFHR1-8555H | Recombinant Human CFHR1 protein(Met1-Arg330), His-tagged | HEK293 | Human | His | Met1-Arg330 |
|
| CFHR1-1289HCL | Recombinant Human CFHR1 cell lysate | Human Cell | Human | Non |
|
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| CFHR1-1000H | Recombinant Human CFHR1 Protein (Glu19-Arg330), C-His tagged | Mammalian cells | Human | His | Glu19-Arg330 |
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| CFHR1-2819H | Recombinant Human CFHR1 protein(132-221aa), His-GST&Myc-tagged | E. coli | Human | N-His-GST&C-Myc | 132-221aa |
|
| CFHR1-764H | Recombinant Human CFHR1 Protein, His-tagged | E.coli | Human | His | Thr205-Lys329 |
|
Involved Pathway
CFHR1 involved in several pathways and played different roles in them. We selected most pathways CFHR1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CFHR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CFHR1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CFHR1 itself. We selected most functions CFHR1 had, and list some proteins which have the same functions with CFHR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CFHR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CFHR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CFHR1.
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References
- Khandelwal, P; Gupta, A; et al. Effect of plasma exchange and immunosuppressive medications on antibody titers and outcome in anti-complement factor H antibody-associated hemolytic uremic syndrome. PEDIATRIC NEPHROLOGY 30:451-457(2015).
- Caesar, JJE; Lavender, H; et al. Competition between antagonistic complement factors for a single protein on N-meningitidis rules disease susceptibility. ELIFE 3:-(2014).
