CERS4
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Official Full Name
ceramide synthase 4 -
Synonyms
CERS4;ceramide synthase 4;LAG1 homolog, ceramide synthase 4 , LAG1 longevity assurance homolog 4 (S. cerevisiae) , LASS4;FLJ12089;Trh1;LAG1 homolog ceramide synthase 4;LAG1 longevity assurance homolog 4;LASS 4;LASS4;LASS4 LAG1 homolog ceramide synthase 4;LASS4_HUMAN;Trh 1;LAG1 homolog, ceramide synthase 4
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- Bovine
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CERS4 involved in several pathways and played different roles in them. We selected most pathways CERS4 participated on our site, such as Sphingolipid metabolism,Metabolic pathways,Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CERS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CYP2C54,POLR3B,CYP3A65,SAT1A.1,SCP2A,SDHDB,DAO1,NAMPTB,GMDS,Cel |
| Sphingolipid signaling pathway | PPP2R2C,PPP2R5B,RAC1,LASS4,MAPK1,FCER1A,PIK3CA,SPHK1,S1PR4,MAPK8 |
| Sphingolipid metabolism | VAPB,LASS4,CERS5,GLTPD1,GALCA,COL4A3BP,SMPD4,SUMF2,CERS2,GLTPA |
Protein Function
CERS4 has several biochemical functions, for example, DNA binding,sphingosine N-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CERS4 itself. We selected most functions CERS4 had, and list some proteins which have the same functions with CERS4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sphingosine N-acyltransferase activity | CERS4A,LASS1,CERS5,LASS5,LASS2,LASS4,CERS2,CERS2A,FAM57B,CERS3B |
| DNA binding | HDGF2,ZFP687,POLR2K,HOXD12A,ZFP746,APEX2,HIST1H3H,HMX4,DHX58,VPS72 |
Interacting Protein
CERS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CERS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CERS4.
ltp_ebvg
Resources
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References
- Ebel, P; Imgrund, S; et al. Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia. BIOCHEMICAL JOURNAL 461:147-158(2014).
