CEACAM3
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Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 3 -
Overview
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. -
Synonyms
CEACAM3;carcinoembryonic antigen-related cell adhesion molecule 3;CGM1;CD66d;CD66d antigen;carcinoembryonic antigen CGM1;nonspecific cross-reacting antigen;carcinoembryonic antigen gene family member 1;CEA;W264;W282;CD66D;MGC119875
Recombinant Proteins
- Human
- Rat
- HEK293
- E.coli
- Insect Cell
- Human Cell
- Mammalian cells
- HEK293T
- E.coli expression system
- His
- His&SUMO
- Non
- Myc&DDK
Involved Pathway
CEACAM3 involved in several pathways and played different roles in them. We selected most pathways CEACAM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CEACAM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CEACAM3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CEACAM3 itself. We selected most functions CEACAM3 had, and list some proteins which have the same functions with CEACAM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CEACAM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEACAM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEACAM3.
Resources
Research Area
ITIM/ITAM Immunoreceptors and Related MoleculesMyeloid Lineage Markers
Immunoglobulin Superfamily CAMs
Epithelial Cell Markers and Intracellular Molecules
CD Antigen (Neutrophils)
Tumor Antigens
Related Services
Related Products
References
- Wakabayashi-Nakao, K; Hatakeyama, K; et al. Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is specifically expressed in medullary thyroid carcinoma cells. BIOMEDICAL RESEARCH-TOKYO 35:237-242(2014).
- Panczyszyn, A; Wieczorek, M; et al. Role of CEACAM in neutrophil activation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 66:574-582(2012).
