CDKL3
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Official Full Name
cyclin-dependent kinase-like 3 -
Overview
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
CDKL3;cyclin-dependent kinase-like 3;NKIAMRE;serine threonine protein kinase NKIAMRE;CDKL3 protein;Cyclin dependent kinase like 3;serine-threonine protein kinase NKIAMRE;serine/threonine-protein kinase NKIAMRE
Recombinant Proteins
- Human
- Rat
- Cynomolgus
- E.coli
- Wheat Germ
- Mammalian Cells
- Sf9 Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
CDKL3 involved in several pathways and played different roles in them. We selected most pathways CDKL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDKL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDKL3 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDKL3 itself. We selected most functions CDKL3 had, and list some proteins which have the same functions with CDKL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GPR125,NR5A1,ROR2,SYF2,CCDC13,LRRC8C,BRAT1,PSMB2,KRTAP19-7,BRK1 |
| ATP binding | SUCLG1,ABCA1B,MCM2,GLYCTK,EPHB2,RPS6KA4,DGKZ,NEK4,CHUK,PRKAG1 |
| protein kinase activity | MMD,SGK2B,TGFBR1B,STK24A,RASSF2,MAPK12A,CSNK1A1,PLK5,NRBP2,PRKCI |
| cyclin-dependent protein serine/threonine kinase activity | CDK9,CDK5R1,CDK11B,CDK10,CDK6,CDK2,ICK,PFTK1,CDKL5,CDK1 |
Interacting Protein
CDKL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDKL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDKL3.
ZBTB14;TRIM27;FXR2;KRTAP10-9;GOLGA2;MTUS2;CCDC155
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