CDK3
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Official Full Name
cyclin-dependent kinase 3 -
Overview
This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. -
Synonyms
CDK3;cyclin-dependent kinase 3;cell division protein kinase 3
Recombinant Proteins
- Human
- Chicken
- Sf9 Insect Cell
- Wheat Germ
- Insect Cell
- E.coli
- Mammalian Cell
- In Vitro Cell Free System
- Insect (sf21)
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDK3/CyclinE1-273H | Recombinant Human CDK3/CyclinE1, GST-tagged, Active | Sf9 Insect Cell | Human | GST |
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| CDK3-1007H | Recombinant Human CDK3 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CDK3-1009H | Active Recombinant Human CDK3 Protein, GST-Tagged | Insect Cell | Human | GST | 1-305;1-395 a.a. |
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| CDK3-215H | Recombinant Human cyclin-dependent kinase 3, His-tagged | E.coli | Human | His | 1-305 a.a. |
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| CDK3-31091TH | Recombinant Human Human CDK3 | Human | Non | Full L. |
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| CDK3-3668C | Recombinant Chicken CDK3 | Mammalian Cell | Chicken | His |
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| CDK3-327HCL | Recombinant Human CDK3 cell lysate | Human | Non |
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| CDK3-3181HF | Recombinant Full Length Human CDK3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 305 amino acids |
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| CDK3-4540HF | Active Recombinant Full Length Human CDK3 Protein, GST-tagged | Insect (sf21) | Human | GST | Full L. 1-305(end) |
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Involved Pathway
CDK3 involved in several pathways and played different roles in them. We selected most pathways CDK3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK3 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK3 itself. We selected most functions CDK3 had, and list some proteins which have the same functions with CDK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CCC2,MARK3,CSNK1G2B,SRPK3,SMC1AL,SLFNL1,ACLY,NEK10,ROS1,UBE2C |
| cyclin-dependent protein serine/threonine kinase activity | PFTK1,MOK,CDKL3,CDK16,CDK12,CDKL1,CDKL5,CDK14,CDK19,CDK13 |
Interacting Protein
CDK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK3.
CDK5;HSP90AB1;CCNE2;dap;PPARA;CDKN3;Cks30A;CycD;bisindolylmaleimide iii;purvalanol b;midostaurin;EIF2AK2;CCNA2;CCNE1;CDK2;STIP1;ARRB2
Resources
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References
- Mayya, V; Rezual, K; et al. Absolute quantification of multisite phosphorylation by selective reaction monitoring mass spectrometry - Determination of inhibitory phosphorylation status of cyclin-dependent kinases. MOLECULAR & CELLULAR PROTEOMICS 5:1146-1157(2006).
- Vogel, L; Baratte, B; et al. Molecular cloning and characterisation of p15(CDK-BP), a novel CDK-binding protein. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1589:219-231(2002).
