CDCA8
-
Official Full Name
cell division cycle associated 8 -
Overview
This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis;and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule;stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this;gene are found on chromosomes 7, 8 and 16. -
Synonyms
CDCA8;cell division cycle associated 8;borealin;BOR;DasraB;FLJ12042;MESRGP;Dasra B;dasra-B;hDasra-B;cell division cycle-associated protein 8;pluripotent embryonic stem cell-related gene 3 protein;FLJ10468
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
CDCA8 involved in several pathways and played different roles in them. We selected most pathways CDCA8 participated on our site, such as Aurora B signaling,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDCA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle, Mitotic | NUPL2,NDC80,NCAPG,NUP50,NCAPG2,NUMA1,MAU2,KIF2C,SET,APITD1 |
| Mitotic Anaphase | MLF1IP,PDS5A,VRK1,CLIP1,ITGB3BP,ZW10,CENPP,CENPE,RCC2,NUF2 |
| Mitotic Prometaphase | PANE1,KNTC1,NDEL1A,CENPK,NUDC,ZWINT,SMC4,SPC25,CENPN,NDEL1 |
| Cell cycle | TSGA14,SMAD3A,GMNN,TP53,FGFR1OP,CDKN1BA,TGFB1,CSNK1D,NIPBLA,MYC |
| Aurora B signaling | EVI5,NDC80,SEPT1,DES,NCAPD2,TACC1,NCAPH,NPM1,INCENP,AURKB |
| RHO GTPase Effectors | KLC3,NOXA1,LIN7B,NCKIPSD,MIS12,SKA1,NDEL1A,NOXO1A,PMF1,MKL1 |
| M Phase | LEMD3,NCAPD3,STAG1,NCAPH2,NCAPH,NSL1,CDCA5,CNEP1R1,CENPO,PMF1 |
| Mitotic Metaphase and Anaphase | MLF1IP,ZW10,ERCC6L,TMPO,SPDL1,PANE1,CENPL,PDS5B,SPC25,WAPAL |
Protein Function
CDCA8 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDCA8 itself. We selected most functions CDCA8 had, and list some proteins which have the same functions with CDCA8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PACS1,CSPP1,CD160,SUB1,CREB5,FGFR3,MID1,VRK2,CEP120,RNF220 |
Interacting Protein
CDCA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDCA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDCA8.
BIRC5;AURKB;BIRC5
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