CDC23
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Official Full Name
cell division cycle 23 homolog -
Overview
APC8 (anaphase-promoting complex subunit 8) is a member of the E3 enzyme family. This protein contains TPR repeats and has a molecular weight of approximately 68 kD. The APC8 protein is located in the nucleus during interphase and the centrosome during me -
Synonyms
CDC23;cell division cycle 23 homolog (S. cerevisiae);CDC23 (cell division cycle 23, yeast, homolog);cell division cycle protein 23 homolog;ANAPC8;anaphase promoting complex subunit 8;APC8;CUT23;cyclosome subunit 8;anaphase-promoting complex subun
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
CDC23 involved in several pathways and played different roles in them. We selected most pathways CDC23 participated on our site, such as Cell cycle,Oocyte meiosis,Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | DHFR,SETB,CDC14AB,E2F5,ANAPC4,CCND2,CCNB3,GINS1,MCM6,B9D2 |
| Ubiquitin mediated proteolysis | UBE2D3,FBXO2,UBE2L3,SMURF1,CUL3,KEAP1B,FLJ11011L,PML,RBX1,ANAPC13 |
| Oocyte meiosis | YWHAE,SLK,CALM2B,RPS6KA3,CUL1,PPP3CB,PPP1CA,RBX1,CUL1A,BTRC |
| Progesterone-mediated oocyte maturation | IGF1RB,ANAPC2,GNAI2A,ANAPC4,ADCY1A,GNAI2,AKT3A,HSP90AA1.2,MAP2K1,PDE3B |
| HTLV-I infection | RRAS,MYBL2,TRP53INP1,SMAD3,SPI1,NFKBIA,LTBR,NFYB,IL2RA,WNT7B |
Protein Function
CDC23 has several biochemical functions, for example, protein binding,ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC23 itself. We selected most functions CDC23 had, and list some proteins which have the same functions with CDC23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | UBE2G1,TTC3,TRIM69,NEDD4L,MYCBP2,BIRC8,WWP2,UBE2G2,DTX3L,RNF43 |
| protein binding | HNF4A,SPOPL,ZGPAT,CCDC9,MATN2,FRAS1,KLHDC3,F3,BLOC1S1,HGD |
Interacting Protein
CDC23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC23 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC23.
CDC27;TRIM27;RBPMS;OPTN;ANAPC16;FLJ34048
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