CD248
-
Official Full Name
CD248 molecule, endosialin -
Overview
Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. -
Synonyms
CD248;CD248 molecule, endosialin;TEM1;CD164L1;endosialin;2610111G01Rik;CD164 sialomucin-like 1;CD248 antigen, endosialin;tumor endothelial marker 1
Recombinant Proteins
- Human
- Canine
- Rhesus macaque
- Mouse
- E.coli
- Mammalian cells
- HEK293
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- GST
- His
- Fc
- hIgG4
- Flag
- His, Fc, Avi
- SUMO and Strep
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CD248-10932H | Recombinant Human CD248, GST-tagged | E.coli | Human | GST | 399-687a.a. | |
| CD248-23H |
Active Recombinant Human CD248 Protein, His-tagged
|
Mammalian cells | Human | His | Gln18-Arg685 |
|
| CD248-1655C |
Recombinant Canine CD248 protein, His-tagged
|
HEK293 | Canine | His | Gln18-Gly687 |
|
| CD248-0758H | Recombinant Human CD248 Protein, GST-Tagged | Wheat Germ | Human | GST | 1-757aa |
|
| CD248-1628R | Recombinant Rhesus Monkey CD248 Protein | HEK293 | Rhesus macaque | His | 18-687 a.a. |
|
| CD248-1629R | Recombinant Rhesus Monkey CD248 Protein, hIgG1-tagged | HEK293 | Rhesus macaque | Fc | 18-687 a.a. |
|
| CD248-1630R | Recombinant Rhesus Monkey CD248 Protein, hIgG4-tagged | HEK293 | Rhesus macaque | hIgG4 | 18-687 a.a. |
|
| CD248-3063M | Recombinant Mouse CD248 Protein | Mammalian Cell | Mouse | His | Full length or partial length |
|
| CD248-731R | Recombinant Rhesus monkey CD248 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His | Full length or partial length |
|
| CD248-315HCL | Recombinant Human CD248 cell lysate | HEK293 | Human | Flag | 1-757aa |
|
| Cd248-01M | Recombinant Mouse Cd248 Protein, His-tagged, Biotinylated | HEK293 | Mouse | His | 18-695aa |
|
| CD248-1111H | Recombinant Human CD248 Protein (Gln18-Glu245), N-His tagged | E.coli | Human | His | Gln18-Glu245 |
|
| CD248-1447M | Recombinant Mouse CD248 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His, Fc, Avi | 18-695aa |
|
| CD248-1447M-B | Recombinant Mouse CD248 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse | His | 18-695aa |
|
| CD248-230H | Recombinant Human CD248 protein, His-tagged | E.coli | Human | His | 21-401 aa |
|
| CD248-2630H | Recombinant Human CD248 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His, Fc, Avi | 18-695aa |
|
| CD248-2630H-B | Recombinant Human CD248 Protein Pre-coupled Magnetic Beads | HEK293 | Human | His | 18-695aa |
|
| CD248-3089HF | Recombinant Full Length Human CD248 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 1-757aa |
|
| Cd248-3533M | Recombinant Mouse Cd248 protein, His-tagged | HEK293 | Mouse | His | Gln18-Leu695 |
|
| CD248-3581H | Recombinant Human CD248 Protein (Gly30-Cys156), C-His tagged | E.coli | Human | His | Gly30-Cys156 |
|
| CD248-5033H | Recombinant Human CD248 protein, His-tagged | HEK293 | Human | His | Gln18-Leu687 |
|
| Cd248-5480M | Recombinant Mouse Cd248 Protein (Val19-Cys156), SUMO and Strep tagged | E.coli | Mouse | SUMO and Strep | Val19-Cys156 |
|
| CD248-557R | Recombinant Rhesus Macaque CD248 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His, Fc, Avi | 1-685aa |
|
| CD248-557R-B | Recombinant Rhesus Macaque CD248 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque | His | 1-685aa |
|
Involved Pathway
CD248 involved in several pathways and played different roles in them. We selected most pathways CD248 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CD248 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CD248 has several biochemical functions, for example, calcium ion binding,carbohydrate binding,extracellular matrix binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD248 itself. We selected most functions CD248 had, and list some proteins which have the same functions with CD248. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | SIGLEC10,GALNT4,KLRC3,ASGR1,GANAB,NOMO3,CANX,GALNT12,PKD1,Mgl2 |
| extracellular matrix binding | VEGFA,ITGAV,SPARC,FBLN2,SPOCK2,DCN,SPP1,CYR61,BGN,ITGA2B |
| molecular_function | FSD1L,ANKRD45,LRBA,TMX2A,SKINT6,NPRL3,DRAM2B,SMIM1,C2orf65,PAGE4 |
| calcium ion binding | MMP11,PCDH2G1,S100A7A,PCDH2G3,DSG1,RHOT1B,CDH24,PCDH1G2,PADI1,GUCA1E |
Interacting Protein
CD248 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD248 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD248.
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References
- Li, CS; Wang, JY; et al. Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer. ONCOTARGET 5:6994-7012(2014).
- Li, CS; Chacko, AM; et al. Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model. CANCER BIOLOGY & THERAPY 15:443-451(2014).
