CAPN11
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Official Full Name
calpain 11 -
Overview
Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008] -
Synonyms
CAPN11;calpain 11;calpain11;calpain-11;CANP 11;calcium-activated neutral proteinase 11
Recombinant Proteins
- Rat
- Human
- Mammalian Cell
- Wheat Germ
- E.coli
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CAPN11-1119R | Recombinant Rat CAPN11 Protein | Mammalian Cell | Rat | His |
|
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| CAPN11-290H | Recombinant Human CAPN11 Protein, GST-tagged | Wheat Germ | Human | GST | 1 a.a. - 702 a.a. |
|
| CAPN11-277HCL | Recombinant Human CAPN11 cell lysate | Human | Non |
|
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| CAPN11-1718H | Recombinant Human CAPN11 protein, His & T7-tagged | E.coli | Human | His&T7 | Phe539~Gly739 |
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| Capn11-1719R | Recombinant Rat Capn11 protein, His & T7-tagged | E.coli | Rat | His&T7 | Met1~Leu214 |
|
| CAPN11-1746HF | Recombinant Full Length Human CAPN11 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 702 amino acids |
|
| CAPN11-783R | Recombinant Rat CAPN11 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CAPN11-783R-B | Recombinant Rat CAPN11 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
CAPN11 involved in several pathways and played different roles in them. We selected most pathways CAPN11 participated on our site, such as Integrin-mediated cell adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Integrin-mediated cell adhesion | SEPP1A,MYLK2,CAPNS1,CAPN10,MAPK4,CAPN5,CAPN9,TNS1,MAPK6,CAPN3A |
Protein Function
CAPN11 has several biochemical functions, for example, calcium ion binding,calcium-dependent cysteine-type endopeptidase activity,peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN11 itself. We selected most functions CAPN11 had, and list some proteins which have the same functions with CAPN11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | NOTCH2NL,EFHA2,CALML4A,MACF1,CALUA,MATN3A,MFGE8B,CCDC167,CAPN13,SPARCL1 |
| calcium-dependent cysteine-type endopeptidase activity | CAPN3B,CAPN5,SOLH,CAPN10,CAPN13,CAPN2B,CAPNS1A,SRI,CAPN3,GCA |
| peptidase activity | TMPRSS12,UCHL3,CAPN3B,OVCH2,KLK5,OTUD7A,TMPRSS11D,DCD,IWS1,KLK1B11 |
Interacting Protein
CAPN11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPN11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPN11.
PRKAR1A;XRCC6;UNG;ANAPC11
Resources
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References
- Zhu, DL; Wang, KL; et al. The c-Jun N-terminal Kinases (JNK)/Mitogen-activated Protein Kinase (MAPK) is Responsible for the Protection of Tanshinol (Danshensu) upon H2O2-Induced L-6 Rat Myoblast Cell Injury. ACTA SCIENTIAE VETERINARIAE 42:-(2014).
- Zhang, ZQ; Zoltewicz, JS; et al. Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products. PLOS ONE 9:-(2014).
