CAPG
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Official Full Name
capping protein (actin filament), gelsolin-like -
Overview
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. -
Synonyms
CAPG;capping protein (actin filament), gelsolin-like;AFCP;macrophage-capping protein;macrophage capping protein;MCP;Actin capping protein GCAP39;Actin regulatory protein CAP G;Capping protein (actin filament) gelsolin like;Capping protein gelsolin like;gCap39;Gelsolin like capping protein;mbh1;Myc basic motif homolog 1;OTTHUMP00000203056;OTTHUMP00000203057;OTTHUMP00000203058;OTTHUMP00000203059;OTTHUMP00000203060;OTTHUMP00000203063;gelsolin-like capping protein;actin regulatory protein CAP-G;actin-regulatory protein C
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Mouse
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CAPG involved in several pathways and played different roles in them. We selected most pathways CAPG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CAPG has several biochemical functions, for example, actin binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPG itself. We selected most functions CAPG had, and list some proteins which have the same functions with CAPG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | VAMP2,PTPRF,KLHL8,LCK,PEX26,GIT2,NDUFA4,PPP4C,CFLAR,FBLN1 |
| protein binding | RARRES3,BUD31,TTPA,SCGB2A2,CSTF1,MYOG,RALBP1,SAP30,PPP2R5A,GAGE2D |
| protein domain specific binding | STX1B,NCK1,TFDP2,YWHABA,TRP63,RAB27B,GABRR2,TBL1X,DRD3,PHRF1 |
| actin binding | MYO10,DAG1,COBL,SHROOM1,CAP2,MYHC4,GAS2L3,LRRC10,INPPL1A,CFL2 |
Interacting Protein
CAPG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPG here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPG.
SIAH1;ACTA1;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;SNW1;CDC5L
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