CADM2
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Official Full Name
cell adhesion molecule 2 -
Overview
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin;(Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the;C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal;proteins. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CADM2;cell adhesion molecule 2;IGSF4D, immunoglobulin superfamily, member 4D;Necl 3;NECL3;nectin like 3;SynCAM2;nectin-like 3;nectin-like protein 3;immunoglobulin superfamily member 4D;immunoglobulin superfamily, member 4D;IGSF4D;Necl-3;synC
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian cells
- Human Cell
- Mammalian Cell
- HEK293
- His
- Non
- Fc
- His&Fc&Avi
Involved Pathway
CADM2 involved in several pathways and played different roles in them. We selected most pathways CADM2 participated on our site, such as Adherens junctions interactions,Cell junction organization,Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CADM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junctions interactions | CDH18A,CDH7,PVRL1A,CTNNA1,JUPA,CDH8,CTNNB2,CADM2A,CDH18,CDH3 |
| Cell junction organization | PVRL2L,RSU1,CDH10,F11R.2,JUPA,CLDN16,LIMS1,CDH5,PARVB,CDH4 |
| Cell-cell junction organization | CDH10A,CDH13,ANG,CDH17,CDH3,PVRL2L,CDH11,CDH8,CLDN20,CADM2A |
| Cell-Cell communication | CDH13,SPTBN1,CLDN4,PVRL1A,CLDN7,CDH12,CDH8,JUPA,FERMT2,PARVB |
Protein Function
CADM2 has several biochemical functions, for example, cell adhesion molecule binding,protein homodimerization activity,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CADM2 itself. We selected most functions CADM2 had, and list some proteins which have the same functions with CADM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | FGF1A,NTF7,LTB,FGF12B,RIPK2,CLCF1,LBP,LAMA3,EPHX2,SSTR3 |
| cell adhesion molecule binding | NPTN,FGFR1,PVRL4,ADAM8,VCAM1,TIGIT,CADM2A,PVRL1,PTPRD,POSTNB |
| receptor activity | ATRN,ADIPOR1B,F2RL1.2,SELS,NR2C2,AGER,NPC1,TNFRSF10A,PVR,VMN1R46 |
| protein homodimerization activity | BOKB,ADIPOQ,DAPK3,HPS4,PKD2,PRMT2,CARS,NCR3,CTBP2,KIAA1804 |
Interacting Protein
CADM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CADM2.
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