CACNA1B
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Official Full Name
calcium channel, voltage-dependent, N type, alpha 1B subunit -
Overview
The N-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit forms the pore through which calcium enters the cell and determines most of the channel's properties. The α1 subunit is also known as the calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B) or Cav2.2 which in humans is encoded by the CACNA1B gene. -
Synonyms
CACNA1B;calcium channel, voltage-dependent, N type, alpha 1B subunit;voltage-dependent N-type calcium channel subunit alpha-1B;BIII;brain calcium channel III;calcium channel, L type, alpha-1 polypeptide;voltage-gated calcium channel subunit alpha Cav2.2;calcium channel, voltage-dependent, L type, alpha 1B subunit;Cav2.2;Cchn1a;AW050276;AW060892;AW822256;alpha(1B)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CACNA1B-5866C | Recombinant Chicken CACNA1B | Mammalian Cells | Chicken | His |
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| CACNA1B-351H | Recombinant Human CACNA1B Protein, His-tagged | E.coli | Human | His | Met1-Asp132 |
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| RFL18024GF | Recombinant Full Length Chicken Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1B(Cacna1B) Protein, His-Tagged | E.coli | Chicken | His | Full L. Full Length (1-159) |
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Involved Pathway
CACNA1B involved in several pathways and played different roles in them. We selected most pathways CACNA1B participated on our site, such as MAPK signaling pathway,Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNA1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | CALM1B,ERBB3,PRKACB,GRIN2C,VDAC2,HTR2A,ATP2B1A,CAMK2G1,HTR2CL1,TACR3A |
| MAPK signaling pathway | PPP3R1B,FGF18A,PRKACBA,MAP2K3,RPS6KA4,PPP3CCA,TGFBR1B,MINK1,FGFR1,CACNB2 |
Protein Function
CACNA1B has several biochemical functions, for example, high voltage-gated calcium channel activity,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNA1B itself. We selected most functions CACNA1B had, and list some proteins which have the same functions with CACNA1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | RBFOX1,MSH2,EP300,NCF2,XRCC5,CORO1A,CD2AP,FOXN3,MAP3K7,DAB2 |
| high voltage-gated calcium channel activity | CACNA1C,CACNB2B,CACNB4B,CACNB3,CACNA1BA,CACNA1SB,CACNA1SA,CACNB3A,CACNB2A,CACNB4A |
Interacting Protein
CACNA1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNA1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNA1B.
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References
- Murakami, M; Nakagawasai, O; et al. Modified behavioral characteristics following ablation of the voltage-dependent calcium channel beta 3 subunit. BRAIN RESEARCH 1160:102-112(2007).
- Romero, PJ; Romero, EA; et al. Voltage-dependent calcium channels in young and old human red cells. CELL BIOCHEMISTRY AND BIOPHYSICS 46:265-276(2006).
