C7
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Official Full Name
complement component 7 -
Overview
C7 is a constituent of the membrane attack complex. C7 binds to C5b forming the C5b-7 complex, where it serves as a membrane anchor. -
Synonyms
C7;complement component 7;complement component C7;OTTHUMP00000197104
Recombinant Proteins
- Human
- Pig
- Rat
- E.coli
- Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS and for antibodies to HCV, HIV-1 and HIV-II)
- Wheat Germ
- HEK293
- Human Cell
- In Vitro Cell Free System
- Human Plasma
- His
- Non
- GST
- Fc
- His&GST
- His&T7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| C7-2439H | Recombinant Human C7 protein, His-tagged | E.coli | Human | His | 310-690 aa | |
| C7-102H |
Active Native Human C7 Protein
|
Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS and for antibodies to HCV, HIV-1 and HIV-II) | Human | Non |
|
|
| C7-0129H | Recombinant Human C7 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| C7-7368H | Recombinant Human C7 protein(Met1-Gln843), hFc-tagged | HEK293 | Human | Fc | 1-843 a.a. |
|
| C7-7369H | Recombinant Human C7 protein(Met1-Gln843), His-tagged | HEK293 | Human | His | Met1-Gln843 |
|
| C7-821H | Recombinant Human C7 protein, His-tagged | E.coli | Human | His | Ser122~His456 |
|
| C7-822P | Recombinant Pig C7 protein, His & GST-tagged | E.coli | Pig | His&GST | Asn255~Asn399 |
|
| C7-823P | Recombinant Pig C7 protein, His & GST-tagged | E.coli | Pig | His&GST | Leu725~Cys838 |
|
| C7-824R | Recombinant Rat C7 protein, His & T7-tagged | E.coli | Rat | His&T7 | Glu1~Ser144 |
|
| C7-1425HCL | Recombinant Human C7 cell lysate | Human Cell | Human | Non |
|
|
| C7-1500HCL | Recombinant Human C7 cell lysate | Human Cell | Human | Non |
|
|
| C7-0585H | Recombinant Human C7 Protein (Ser122-His456), His-tagged | E.coli | Human | His | Ser122-His456 |
|
| C7-2715HF | Recombinant Full Length Human C7 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 843 amino acids |
|
| C7-56H | Native Human Complement C7 | Human Plasma | Human | Non |
|
Involved Pathway
C7 involved in several pathways and played different roles in them. We selected most pathways C7 participated on our site, such as Complement and coagulation cascades,Prion diseases,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with C7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prion diseases | PRKACA,PRNP,FYN,C8G,PRKACB,IL1B,IL6,PRKACG,ELK1,MAPK1 |
| Complement and coagulation cascades | C8B,TFPI,GM5077,F10,C1RA,CFH,PLAT,C4BP,C6,SERPINE1 |
| Systemic lupus erythematosus | C1R,HIST1H4F,HIST1H4A,C5,CD40LG,HIST1H4C,GM14479,HIST1H2BI,HLA-DRB3,C2 |
Protein Function
C7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C7 itself. We selected most functions C7 had, and list some proteins which have the same functions with C7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
C7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C7 here. Most of them are supplied by our site. Hope this information will be useful for your research of C7.
q7ard3_yerpe;q9wmx2-pro_0000037547
Resources
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References
- Moayeri, M; Leysath, CE; et al. A Heterodimer of a VHH (Variable Domains of Camelid Heavy Chain-only) Antibody That Inhibits Anthrax Toxin Cell Binding Linked to a VHH Antibody That Blocks Oligomer Formation Is Highly Protective in an Anthrax Spore Challenge Model. JOURNAL OF BIOLOGICAL CHEMISTRY 290:6584-6595(2015).
- Tiezzi, F; Parker-Gaddis, KL; et al. A Genome-Wide Association Study for Clinical Mastitis in First Parity US Holstein Cows Using Single-Step Approach and Genomic Matrix Re-Weighting Procedure. PLOS ONE 10:-(2015).
