C1QTNF5
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Official Full Name
C1q and tumor necrosis factor related protein 5 -
Overview
This gene encodes a member of the a member of the C1q/tumor necrosis factor superfamily. The encoded protein may be a component of basement membranes and may play a role in cell adhesion. This gene is contained entirely within the 3' UTR of the membrane frizzled-related protein gene on chromosome 11q23 and both genes are expressed from a bicistronic transcript. Mutations in this gene have been associated with late-onset retinal degeneration. -
Synonyms
C1q and tumor necrosis factor related protein 5;C1QTNF5;Complement C1q tumor necrosis factor related protein 5 precursor;LORD;CTRP5;DKFZp586B0621;FLJ30570
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
C1QTNF5 involved in several pathways and played different roles in them. We selected most pathways C1QTNF5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QTNF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
C1QTNF5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C1QTNF5 itself. We selected most functions C1QTNF5 had, and list some proteins which have the same functions with C1QTNF5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
C1QTNF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QTNF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QTNF5.
Resources
Research Area
Serine Proteases and RegulatorsAdipocytokines
Epithelial Cell Markers and Intracellular Molecules
Classical Complement Pathway
Related Services
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References
- Jacobson, SG; Cideciyan, AV; et al. Late-Onset Retinal Degeneration Caused by C1QTNF5 Mutation: Sub-Retinal Pigment Epithelium Deposits and Visual Consequences. JAMA OPHTHALMOLOGY 132:1252-1255(2014).
- Tu, XY; Palczewski, K; et al. The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements. JOURNAL OF STRUCTURAL BIOLOGY 186:86-94(2014).
