BUB1B

  • Official Full Name

    budding uninhibited by benzimidazoles 1 homolog beta

  • Overview

    The Mitotic Checkpoint Complex (MCC), which contains Bub1, Bub1b, Bub3, Mad2, and Cdc20, controls chromosome segregation and monitors kinetochore-microtubule interactions (1). During mitosis, the MCC complex inhibits the ubiquitin ligase activity of the A

  • Synonyms

    BUB1B;budding uninhibited;budding uninhibited by benzimidazoles 1 (yeast homolog), beta;mitotic checkpoint serine/threonine-protein kinase BUB1 beta;Bub1A;BUBR1;MAD3L;SSK1;mitotic checkpoint kinase MAD3L;MAD3/BUB1-related protein kinase;hBUBR1

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • E.coli
  • Sf9 Insect Cell
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Insect (sf21)
  • In Vitro Cell Free System
  • GST
  • Non
  • His
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
BUB1B-10335H Recombinant Human BUB1B, GST-tagged E.coli Human GST C-term-333a.a.
BUB1B-1371H Active Recombinant Human BUB1B, GST-tagged Sf9 Insect Cell Human GST 613 aa-end
BUB1B-26124TH Recombinant Human BUB1B Wheat Germ Human Non 130 amino acids
BUB1B-27105TH Recombinant Human BUB1B Wheat Germ Human Non 1050 amino acids
BUB1B-5973C Recombinant Chicken BUB1B Mammalian Cell Chicken His
BUB1B-8382HCL Recombinant Human BUB1B 293 Cell Lysate HEK293 Human Non
BUB1B-465H Recombinant Human BUB1B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
BUB1B-4915HF Active Recombinant Full Length Human BUB1B Protein, GST-tagged Insect (sf21) Human GST Full L. 1-1050(end)
BUB1B-59HF Recombinant Full Length Human BUB1B Protein In Vitro Cell Free System Human Full L. 1050 amino acids
Bub1b-726M Recombinant Mouse Bub1b Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    BUB1B involved in several pathways and played different roles in them. We selected most pathways BUB1B participated on our site, such as Cell cycle,HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with BUB1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell cycle GADD45AB,CNEP1R1,CSNK1D,SPO11,TUBB4A,DYNC1H1,BRCC3,NUDC,CDC25B,MAD1L1
    HTLV-I infection ANAPC5,NRP1,CCND2,FZD9,WNT2B,HLA-DMA,CCNB2,HLA-DRA,FZD2,KAT2A

    Protein Function

    BUB1B has several biochemical functions, for example, ATP binding,protein binding,protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BUB1B itself. We selected most functions BUB1B had, and list some proteins which have the same functions with BUB1B. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SLC35A2,DYDC1,DDX18,C10orf62,AP4B1,WDR4,RSPO1,COA3,DTNB,LGALS9C
    ATP binding WEE2,HNRNPU,CAMK4,SMARCA5,DDX3,DGKA,ABCD2,CLK2B,AKT2L,ORC4
    protein kinase activity CAMK2D2,CCL2,PDK3,ZNF143B,LMTK3,PKZ,PRKACBA,VRK1,MAP2K5,CHEK1
    protein serine/threonine kinase activity SNRKB,MYO3A,VRK1,PLK1,OXSR1B,MAP3K10,TESK2,CAMK2A,STK35L,EIF2AK3

    Interacting Protein

    BUB1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BUB1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BUB1B.

    CDC20;BUB3

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