BRWD1

  • Official Full Name

    bromodomain and WD repeat domain containing 1

  • Overview

    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

  • Synonyms

    BRWD1;bromodomain and WD repeat domain containing 1;C21orf107, chromosome 21 open reading frame 107 , WD repeat domain 9 , WDR9;bromodomain and WD repeat-containing protein 1;FLJ11315;N143;Bromodomain and WD repeat domain containing protein 1;BRWD1_HUMAN;C21orf107;cAMP response element binding and beta tranducin family;chromosome 21 open reading frame 107;Response element binding and beta tranducin family like;Transcriptional unit N143;WD repeat protein;WD repeat protein WDR9 form2;WD repeat-containing protein 9;WDR9;WD repeat protein WDR9-form2

Recombinant Proteins

  • Human
  • E.coli
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His&Flag
  • His
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
BRWD1-167H Recombinant Human BRWD1, GST-tagged E.coli Human GST 1310-1426 a.a.
BRWD1-355H Recombinant Human BRWD1 Protein, GST-tagged Wheat Germ Human GST
BRWD1-38H Recombinant Human BRWD1, His&FLAG-tagged E.coli Human His&Flag 1310-1430 a.a.
BRWD1-62H Recombinant Human BRWD1 protein, GST-tagged E.coli Human GST 1310-1430
BRWD1-63H Recombinant Human BRWD1 protein, His-tagged E.coli Human His 1310-1430
BRWD1-186HCL Recombinant Human BRWD1 cell lysate Human Non
BRWD1-3823HF Recombinant Full Length Human BRWD1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 120 amino acids

    Involved Pathway

    BRWD1 involved in several pathways and played different roles in them. We selected most pathways BRWD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BRWD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    BRWD1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by BRWD1 itself. We selected most functions BRWD1 had, and list some proteins which have the same functions with BRWD1. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function FAM40A,PALM3,LHFPL5B,TMEM110,BTNL1,MUC12,TMEM150A,MTUS1A,PPL,PLEKHD1

    Interacting Protein

    BRWD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRWD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRWD1.

    mutT7;UBXN7;CBX6;MYC;Lin28a;MMGT1

    Resources

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