BOK
-
Official Full Name
BCL2-related ovarian killer -
Overview
Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok -
Synonyms
BOK;BCL2-related ovarian killer;bcl-2-related ovarian killer protein
Recombinant Proteins
- Rat
- Mouse
- Human
- Rhesus macaque
- Chicken
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- GST
- His&Fc&Avi
Involved Pathway
BOK involved in several pathways and played different roles in them. We selected most pathways BOK participated on our site, such as Apoptosis,Apoptosis Modulation and Signaling,TP53 network, which may be useful for your reference. Also, other proteins which involved in the same pathway with BOK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Apoptosis Modulation and Signaling | BIK,HRK,CRADD,CASP2,CDKN2A,PTRH2,PTPN13,DAXX,BAG3,BCL2L10 |
| TP53 network | OTX2 |
| Apoptosis | IL1R1,AIFM1,VIML,IRF4,HMGB2,PRKACAA,TICAM1,CFLARA,RIPK1L,DIABLO |
Protein Function
BOK has several biochemical functions, for example, BH domain binding,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BOK itself. We selected most functions BOK had, and list some proteins which have the same functions with BOK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| BH domain binding | BCL2L2,BAK1,Bcl2a1b,BIK,BCL2A1A |
| protein heterodimerization activity | HIST1H4B,SFRP5,SOS1,HIST1H4H,ODZ4,IL12A,PKNOX1,PIK3R2,NFE2L2A,HIST1H4E |
| protein homodimerization activity | SERPINF2,LGALS6,CADM1B,XPNPEP1,CD8A,TYW5,NRF1,PRLR,AOC3,GRPEL2 |
| protein binding | FBN1,TSG101,ACAT2,RIN3,EMG1,TEK,FAM111A,HIST1H4B,IFNA4,SLC25A6 |
Interacting Protein
BOK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BOK here. Most of them are supplied by our site. Hope this information will be useful for your research of BOK.
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