BHLHE22
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Official Full Name
basic helix-loop-helix family, member e22 -
Overview
BHLHE22 belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. These proteins function as dimers and bind to an E-box DNA sequence (CANNTG). BHLHE22 is expressed exclusively in the central nervous system and retina (Xu et al., 2002 [PubMed 12213201]).[supplied by OMIM, Jul 2010] -
Synonyms
BHLHE22;basic helix-loop-helix family, member e22;Beta3;BHLHB5;CAGL85;TNRC20;class E basic helix-loop-helix protein 22;trinucleotide repeat containing 20;class B basic helix-loop-helix protein 5;trinucleotide repeat-containing gene 20 protein;basic helix-loop-helix domain containing, class B, 5
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BHLHE22-3611H | Recombinant Human BHLHE22 protein, His-tagged | E.coli | Human | His | 1-225 aa | |
| BHLHE22-11192Z | Recombinant Zebrafish BHLHE22 | Mammalian Cell | Zebrafish | His |
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| BHLHE22-211H | Recombinant Human BHLHE22 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BHLHE22-2396M | Recombinant Mouse BHLHE22 Protein | Mammalian Cell | Mouse | His |
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| BHLHE22-1028M | Recombinant Mouse BHLHE22 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| BHLHE22-1028M-B | Recombinant Mouse BHLHE22 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| BHLHE22-1620HF | Recombinant Full Length Human BHLHE22 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 381 amino acids |
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Involved Pathway
BHLHE22 involved in several pathways and played different roles in them. We selected most pathways BHLHE22 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BHLHE22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
BHLHE22 has several biochemical functions, for example, DNA binding,metal ion binding,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BHLHE22 itself. We selected most functions BHLHE22 had, and list some proteins which have the same functions with BHLHE22. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | KLF12,PPP4CA,ADAT1,TRIM55B,GM5077,AIFM3,NRP2B,PEG3,TRIM43A,ZNF207B |
| sequence-specific DNA binding | LONP1,PGBD1,LMX1B,OTPA,HOXC4A,ZIC3,HOXD12,FOXE1,ZNF498,ZNF187 |
| nucleic acid binding | FOXP1B,RBM14B,TIGD5,BICC1,HNRNPA3,GLIS3,EIF4A1A,RBM14A,PNLDC1,DBF4B |
| transcription factor activity, sequence-specific DNA binding | CREB3L3L,POUV,HES1,ZFP37,ZNF561,TCF4,PFDN1,SALL4,FOXN2,HOXA3A |
| DNA binding | POLR2H,MKXB,ZFP276,TFEC,ZBTB20,AHR,TCF7L1A,ZFP580,HDGFRP2,MTERFD1 |
Interacting Protein
BHLHE22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BHLHE22 here. Most of them are supplied by our site. Hope this information will be useful for your research of BHLHE22.
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