BHLHA15
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Official Full Name
basic helix-loop-helix family, member a15 -
Overview
Class A basic helix-loop-helix protein 15 is a protein that in humans is encoded by the BHLHA15 gene. -
Synonyms
BHLHA15;basic helix-loop-helix family, member a15;class A basic helix-loop-helix protein 15;intestine and stomach expression 1;Basic helix loop helix domain containing class B 8;Basic helix loop helix family member a15;BHA15_HUMAN;bHLHB8;Class B basic helix-loop-helix protein 8;Class II bHLH protein MIST1;MIST 1;MIST-1;MIST1;Muscle;Muscle intestine and stomach expression 1;OTTMUSP00000031081;muscle, intestine and stomach expression 1;basic helix-loop-helix domain containing, class B, 8;1810009C13Rik
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- E.coli
- GST
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
BHLHA15 involved in several pathways and played different roles in them. We selected most pathways BHLHA15 participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with BHLHA15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Maturity onset diabetes of the young | INS,HNF1B,INS1,PDX1,HNF1A,NKX6-1,RFX6,NKX6,HNF4A,HES1 |
Protein Function
BHLHA15 has several biochemical functions, for example, DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BHLHA15 itself. We selected most functions BHLHA15 had, and list some proteins which have the same functions with BHLHA15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ISL1L,TAF11,LCOR,RXRAB,DBN1,CHD4A,POLA1,ZFP541,POLN,H3F3B.1 |
| protein dimerization activity | MESPAA,TXLNB,KIF9,SOHLH2,NUP210,HER8A,MEF2B,HER3,OLIG3,EBF3A |
| RNA polymerase II regulatory region sequence-specific DNA binding | ONECUT3,XBP1,GATA2A,MNT,NR1I3,JARID2,CGGBP1,AEBP1,ZSCAN2,ARHGAP35 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | IKZF3,NEUROD2,OVOL2,SLAMF7,ZGLP1,LEF1,LMO2,MAFK,MYF5,ALX4 |
| protein homodimerization activity | ABCG2,VPS24,UPK1A,TPD52,MCL1,PVRL1,Flt3l,GPD1B,UGT1A1,RAB11FIP4B |
Interacting Protein
BHLHA15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BHLHA15 here. Most of them are supplied by our site. Hope this information will be useful for your research of BHLHA15.
Resources
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References
- Jin, RU; Mills, JC; et al. RAB26 coordinates lysosome traffic and mitochondrial localization. JOURNAL OF CELL SCIENCE 127:1018-1032(2014).
- Hale, MA; Swift, GH; et al. The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. DEVELOPMENT 141:3123-3133(2014).
