BDH2
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Official Full Name
3-hydroxybutyrate dehydrogenase, type 2 -
Overview
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase. -
Synonyms
BDH2;3-hydroxybutyrate dehydrogenase, type 2;dehydrogenase/reductase (SDR family) member 6 , DHRS6;3-hydroxybutyrate dehydrogenase type 2;FLJ13261;PRO20933;SDR15C1;short chain dehydrogenase/reductase family 15C;member 1;UCPA OR;UNQ6308;3 hydroxybutyrate dehydrogenase type 2;BDH 2;BDH2_HUMAN;Dehydrogenase/reductase (SDR family) member 6;Dehydrogenase/reductase SDR family member 6;DHRS6;EFA6R;Oxidoreductase ucpA;R beta hydroxybutyrate dehydrogenase;R-beta-hydroxybutyrate dehydrogenase;Short chain dehydrogenase/reductase family 15C member 1;short chain dehydrogenase/reductase family 15C, member 1;UCPA-OR
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- Mammalian cells
- HEK293T
- E. coli
- His
- GST
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
BDH2 involved in several pathways and played different roles in them. We selected most pathways BDH2 participated on our site, such as Synthesis and degradation of ketone bodies,Butanoate metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with BDH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | PFKM,PDXK,ATP6V1A,AK5,CYP2C19,B4GALT4,MIBP,NDUFB3,NDUFV1,AMD1 |
| Butanoate metabolism | DHRS13L1,BDH1,EHHADH,OXCT2,ACSM4,HMGCL,HADH,OXCT2A,ACADS,HADHAB |
| Synthesis and degradation of ketone bodies | OXCT1A,OXCT2A,OXCT2,OXCT2B,HMGCLL1,OXCT1B,HMGCL,BDH1,ACAT2,ACAT1 |
Protein Function
BDH2 has several biochemical functions, for example, 3-hydroxybutyrate dehydrogenase activity,NAD binding,oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by BDH2 itself. We selected most functions BDH2 had, and list some proteins which have the same functions with BDH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAD binding | IDH3A,ADH1,AOX1,HSD11B2,ME2,NDUFS2,GAPDHS,UGDH,HSD17B10,GRHPR |
| 3-hydroxybutyrate dehydrogenase activity | BDH1 |
| oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | TM7SF2,DHCR24,SRD5A3,LBR |
Interacting Protein
BDH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDH2.
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