BCMO1
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Official Full Name
beta-carotene 15,15-monooxygenase 1 -
Overview
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. -
Synonyms
BCMO1;beta-carotene 15,15-monooxygenase 1;BCDO, BCDO1, beta carotene 15, 15 dioxygenase 1;beta,beta-carotene 15,15-monooxygenase;BCMO;FLJ10730;beta-carotene dioxygenase 1;beta-carotene 15, 15-dioxygenase 1;BCO;BCDO;BCO1;BCDO1
Recombinant Proteins
- Human
- Chicken
- Rat
- E.coli
- Wheat Germ
- HEK293
- Mammalian Cell
- In Vitro Cell Free System
- Mamanlian cells
- His
- GST
- Myc&DDK
- Non
- Flag
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BCMO1-10192H | Recombinant Human BCMO1, His-tagged | E.coli | Human | His | 199-547a.a. | |
| BCMO1-170H | Recombinant Human BCMO1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BCMO1-171H | Recombinant Human BCMO1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BCMO1-26H | Recombinant Human BCMO1 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| BCMO1-6203C | Recombinant Chicken BCMO1 | Mammalian Cell | Chicken | His |
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| BCMO1-962R | Recombinant Rat BCMO1 Protein | Mammalian Cell | Rat | His |
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| BCMO1-8474HCL | Recombinant Human BCMO1 293 Cell Lysate | HEK293 | Human | Non |
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| BCMO1-132H | Recombinant Human BCMO1 Protein, His-tagged | E.coli | Human | His | 6-206 a.a. |
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| BCMO1-1554HF | Recombinant Full Length Human BCMO1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 547 amino acids |
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| BCMO1-2006HFL | Recombinant Full Length Human BCMO1 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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| BCMO1-620R | Recombinant Rat BCMO1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| BCMO1-620R-B | Recombinant Rat BCMO1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
BCMO1 involved in several pathways and played different roles in them. We selected most pathways BCMO1 participated on our site, such as Retinol metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | GPAT2,NDUFA11,NT5C1A,LASS4,SEPHS1,HAAO,HSD17B10,B4GALT7,B4GALNT1,P4HA1B |
| Retinol metabolism | ALDH1A1,RPE65,SDR16C5A,BCO1,DHRS3,UGT1A1,ADH2-1,AOX2P,CYP26B1,CYP1A |
Protein Function
BCMO1 has several biochemical functions, for example, beta-carotene 15,15-monooxygenase activity,metal ion binding,monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCMO1 itself. We selected most functions BCMO1 had, and list some proteins which have the same functions with BCMO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZFP628,WBP7,MOB3A,IKZF4,ZDHHC20A,ECE1,HBB-BH1,ANG3,ITGA10,AGBL1 |
| beta-carotene 15,15-monooxygenase activity | BCO1 |
| monooxygenase activity | CYP4F18,CYP4A10,CYP21A1,CYP3A7,CYP1C2,CYP1B1,CYP2AA9,CYP2B19,CYP4A12A,YWHAQB |
Interacting Protein
BCMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCMO1.
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References
- Zubair, N; Kooperberg, C; et al. Genetic Variation Predicts Serum Lycopene Concentrations in a Multiethnic Population of Postmenopausal Women. JOURNAL OF NUTRITION 145:187-192(2015).
- Yamaguchi, N; Sunto, A; et al. Competitive regulation of human intestinal beta-carotene 15,15 '-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear factor (HNF)-1 alpha and HNF-4 alpha. LIFE SCIENCES 119:34-39(2014).
