BAAT

  • Official Full Name

    bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)

  • Overview

    The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.

  • Synonyms

    BAAT;bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase);bile acid Coenzyme A: amino acid N acyltransferase (glycine N choloyltransferase);bile acid-CoA:amino acid N-acyltransferase;BAT;FLJ20300;BACAT;Bile acid CoA:amino acid N acyltransferase;Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase;Bile acid Coenzyme A: amino acid N acyltransferase;Glycine N choloyltransferase;Long chain fatty acyl CoA hydrolase;MGC104432;OTTHUMP00000021802;long-chain fatty-acyl-CoA hydrolase;bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
BAAT-10119H Recombinant Human BAAT, GST-tagged E.coli Human GST 1-418a.a.
BAAT-042H Recombinant Human BAAT protein, GST-tagged Wheat Germ Human GST
BAAT-2262M Recombinant Mouse BAAT Protein Mammalian Cell Mouse His
BAAT-927R Recombinant Rat BAAT Protein Mammalian Cell Rat His
BAAT-8533HCL Recombinant Human BAAT 293 Cell Lysate HEK293 Human Non
BAAT-1425H Recombinant Human BAAT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
BAAT-585R Recombinant Rat BAAT Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
BAAT-585R-B Recombinant Rat BAAT Protein Pre-coupled Magnetic Beads HEK293 Rat
Baat-686M Recombinant Mouse Baat Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
BAAT-944M Recombinant Mouse BAAT Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
BAAT-944M-B Recombinant Mouse BAAT Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    BAAT involved in several pathways and played different roles in them. We selected most pathways BAAT participated on our site, such as Primary bile acid biosynthesis,Taurine and hypotaurine metabolism,Biosynthesis of unsaturated fatty acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with BAAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Taurine and hypotaurine metabolism GGT1A,GAD1B,ADOB,CDO1,GAD1,GGT7,GGT5,ADO,CSAD,GAD2
    Bile secretion AQP9,NR1H4,SLC22A8,ABCB1A,SLCO1A2,CFTR,ATP1A1,ATP1B4,SLCO1A5,SULT2A1
    Peroxisome CRATB,ABCD4,NUDT12,FAR2,HMGCLL1,NOS2A,PRDX5,DDO,ACAA1,HACL1
    Metabolic pathways LPIN1,ST6GALNAC1,NDUFS6,COX6C,CMPK2,PGS1,ALLC,ETNK2,ACSM5,ALDH9A1A.1
    Primary bile acid biosynthesis CH25H,CYP39A1,CYP46A1.2,SCP2,CYP46A1.4,AKR1D1,CYP46A1.1,ACOX2,CYP46A1.3,CYP8B1
    Biosynthesis of unsaturated fatty acids ACOT1,PECR,ELOVL5,ACAA1,SCD5,FADS1,HSD17B12,HSD17B12B,ACOX3,HADHAB

    Protein Function

    BAAT has several biochemical functions, for example, N-acyltransferase activity,carboxylic ester hydrolase activity,glycine N-choloyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BAAT itself. We selected most functions BAAT had, and list some proteins which have the same functions with BAAT. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CENPI,CSRNP2,CDKN2C,TAL1,STX3,WBP1L,RFX5,PDCD1,TBC1D5,ARF4
    N-acyltransferase activity HRASLS5,MBOAT4,NAT14,MBOAT1,CML2,Acnat1,CML5,HHAT,DGAT2L6,MBOAT7
    carboxylic ester hydrolase activity CES1,PNPLA7,Cel,CES2,FAM135B,ACOT10,Aadacl3,LIPI,AADACL2,ABHD11
    medium-chain acyl-CoA hydrolase activity ACOT8
    receptor binding HAMP,HACL1,MAP7,CD276,ITGA1,NRXN1,ABL2,LYN,HLA-G,CSK
    palmitoyl-CoA hydrolase activity ACOT7,THEM5,ACOT5,ACOT2,ACOT8,THEM4,GNPAT,PPT1,ACOT1

    Interacting Protein

    BAAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BAAT here. Most of them are supplied by our site. Hope this information will be useful for your research of BAAT.

    GOLGA8F;GOLGA8DP;AURKA;BUB1;BCL10;ERBB2;RB1;ODC1;SRC;MCC;APC;CTNNA1;MLH1;PTPRJ;SMAD4;PDGFRL

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All BAAT Products

    Required fields are marked with *

    My Review for All BAAT Products

    Required fields are marked with *