B4GALNT1
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Official Full Name
beta-1,4-N-acetyl-galactosaminyl transferase 1 -
Overview
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. -
Synonyms
B4GALNT1;beta-1,4-N-acetyl-galactosaminyl transferase 1;beta-1,4 N-acetylgalactosaminyltransferase 1;beta1 4GalNAc T;GD2 synthase;GM2 synthase;(N acetylneuraminyl) galactosylglucosylceramide;Beta 1 4 N acetyl galactosaminyl transferase 1;Beta 1 4 N acetylgalactosaminyltransferase 1;GALGT;GalNAc T;GALNACT;GM2/GD2 synthase;SIAT 2;SIAT2;UDP Gal:betaGlcNAc beta 1 4 N acetylgalactosaminyltransferase transferase 1;UDP N acetyl alpha D galactosamine:(N acetylneuraminyl) galactosylglucosylceramide N acetylgalactosaminyltransferase;GalNAc-T;beta1,4GalNAc-T;beta1-4GalNAc-T;GD2 synthase, GM2 synthase;(N-acetylneuraminyl)-galactosylglucosylceramide;UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1;UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| B4GALNT1-026H | Recombinant Human B4GALNT1 protein, GST-tagged | Wheat Germ | Human | GST |
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| B4GALNT1-920R | Recombinant Rat B4GALNT1 Protein | Mammalian Cell | Rat | His |
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| B4GALNT1-2110HCL | Recombinant Human B4GALNT1 cell lysate | Human | Non |
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| B4GALNT1-1645HF | Recombinant Full Length Human B4GALNT1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 328 amino acids |
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| B4GALNT1-578R | Recombinant Rat B4GALNT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| B4GALNT1-578R-B | Recombinant Rat B4GALNT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
B4GALNT1 involved in several pathways and played different roles in them. We selected most pathways B4GALNT1 participated on our site, such as Glycosphingolipid biosynthesis - ganglio series,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with B4GALNT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | UGT1A4,HSD17B10,CES1C,NDUFB9,SDSL,ADO,HYAL4,ARSB,ASL,MT-ND1 |
| Glycosphingolipid biosynthesis - ganglio series | ST8SIA1,HEXB,SLC33A1,ST3GAL2,ST3GAL1,B3GALT4,GLB1,ST8SIA5,ST6GALNAC6,HEXA |
Protein Function
B4GALNT1 has several biochemical functions, for example, (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B4GALNT1 itself. We selected most functions B4GALNT1 had, and list some proteins which have the same functions with B4GALNT1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
B4GALNT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B4GALNT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of B4GALNT1.
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