B3GNT1
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Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 -
Synonyms
B3GNT1;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1;B3GNT6, UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 6;N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase;B3GN T1;BETA3GNTI;iGAT;iGNT;iGnT;poly-N-acetyllactosamine extension enzyme;i-beta-1,3-N-acetylglucosaminyltransferase;beta-1,3-N-acetylglucosaminyltransferase bGnT-6;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6;B3GNT6;B3GN-T1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
B3GNT1 involved in several pathways and played different roles in them. We selected most pathways B3GNT1 participated on our site, such as Glycosaminoglycan biosynthesis - keratan sulfate,Glycosaminoglycan metabolism,Glycosphingolipid biosynthesis - lacto and neolacto series, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GNT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Metabolism | OAZ3,Alb,OXSR1,CYP2R1,ARSK,KCNC2,Sult2a6,NUDT3,ARL2BP,CSNK1G2 |
Keratan sulfate biosynthesis | B3GNT2A,B3GNT2,PRELP,SLC35D2,KERA,B3GNT3,OGN,ST3GAL3A,OMD,FMODA |
Glycosaminoglycan biosynthesis - keratan sulfate | CHST4,B3GNT2,B3GNT7,ST3GAL2,FUT8,B4GALT3,Chst5,B4GALT2,B3GNT2B,ST3GAL3B |
Metabolism of carbohydrates | SLC5A9,SLC25A12,GCKR,NHLRC1,AGL,ST3GAL3A,SLC26A2,B3GNT2A,KHK,SLC35B2 |
Glycosphingolipid biosynthesis - lacto and neolacto series | ST3GAL6,B3GALT2,GGTA1,B3GNT3,B3GNT5,B3GNT5A,ST8SIA1,B3GNTL2,ST3GAL3B,FUT7 |
Glycosaminoglycan metabolism | CSPG5B,SLC26A2,B3GNT2A,GLB1L,MAPK1IP1L,GPC1B,B3GNT2,OMD,Gpc2,OGN |
Keratan sulfate/keratin metabolism | ST3GAL3A,B3GNT2,FMODA,SLC35D2,B3GNT3,OMD,GLB1L,B3GNT2A |
Metabolic pathways | POLR2C,CHIA,SAT1A.2,HSD17B3,LASS1,B4GALNT1,QDPR,PLCB4,ACSL1B,ALG2 |
Protein Function
B3GNT1 has several biochemical functions, for example, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity,NOT N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity,glucuronosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GNT1 itself. We selected most functions B3GNT1 had, and list some proteins which have the same functions with B3GNT1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
metal ion binding | NRP1A,BIRC5,ZNF524,TMEM129,ME3,CSGALNACT1,MARCH4,SLC25A25A,ZFP775,DGKD |
glucuronosyltransferase activity | UGT2A3,UGT2B3,UGT5B3,UGT2A4,CSGALNACT1,B3GAT3,UGT5B4,EXT2,UGT8,LARGE |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity | B3GNT3,B3GNT4,GCNT2,B3GNT2 |
Interacting Protein
B3GNT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GNT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GNT1.
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References
- Haider, S; Wang, J; et al. A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. GENOME MEDICINE 6:-(2014).
- Neto, OA; Tassy, O; et al. Integrative Data Mining Highlights Candidate Genes for Monogenic Myopathies. PLOS ONE 9:-(2014).