ATP5D
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Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit -
Overview
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified. -
Synonyms
ATP5D;ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit;ATP synthase subunit delta, mitochondrial;F-ATPase delta subunit;mitochondrial ATP synthase, delta subunit;mitochondrial ATP synthase complex delta-subunit precusor
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- HEK293
- Yeast
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&SUMO
- His&Fc&Avi
- His&Myc
Involved Pathway
ATP5D involved in several pathways and played different roles in them. We selected most pathways ATP5D participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alzheimers disease | COX6C,NDUFS7,APP,ITPR1,GRIN2C,COX4I1,COX8A,IDE,LPL,ITPR2 |
| Metabolic pathways | POLR2D,ACSL1A,IDH1,MTMR7,B3GALT6,PAH,SUCLG2,PMVK,CYP2C50,GLCE |
| Huntingtons disease | UQCR10,COX5B,VDAC3,DCTN4,NDUFB9,DNAH11,COX7B2,ATP5G1,DNALI1,POLR2J3 |
| Oxidative phosphorylation | ATP6V0A2,NDUFV1,NDUFB9,COX7B2,NDUFA7,ATP6V1C2,SDHDA,ATP5C1,COX15,COX7A2L |
| Parkinsons disease | NDUFC1,Atp5g2,COX7A1,NDUFB9,ATP5A1,UQCRH,COX7A2L,GNAI2,NDUFA3,DRD1A |
Protein Function
ATP5D has several biochemical functions, for example, contributes_to ADP binding,contributes_to ATP binding,contributes_to ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5D itself. We selected most functions ATP5D had, and list some proteins which have the same functions with ATP5D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | CPNE1,SLC5A3A,RBP4L,SLC12A10.2,NUP98,SLC2A15B,CHP,SLCO2B1,SLC17A9B,STEAP1 |
| contributes_to ADP binding | MSH2,MSH6 |
| contributes_to ATP binding | ATP1A2,ABCG8,ATP1B1,MSH6,MSH2,SFRP5 |
| proton-transporting ATPase activity, rotational mechanism | ATP6V0B,ATP6V1E1B,ATP6V0CA,ATP6V0E1,ATP6V1C1,ATP6V0A1A,ATP6V0A1,ATP6V0A4,ATP5E,ATP6V1AA |
| transmembrane transporter activity | SLC22A1,SLC2A15A,ATP5J,SLC2A15B,SLC22A7A,SLC22A7B.1,SLC22A23,SLC22A13,SLC22A16,SLC17A9B |
| contributes_to proton-transporting ATP synthase activity, rotational mechanism | ATP5F1 |
| contributes_to ATPase activity | ATP5L,SFRP5,RUVBL2,ATP1A2,ATP6V1H,ATP5F1,ATP5E,ATP5C1,MSH2,RFC3 |
Interacting Protein
ATP5D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5D here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5D.
vpu;SGK1;RIPK2;EIF1B;ATP5F1;PSMD6;ATG5;TTN;FRMD3;ssrna_ug;Kcnk1;BLK;Atp5a1;P;SLC38A1
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