ATG4D
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Official Full Name
autophagy-related 4D (yeast) -
Overview
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, a -
Synonyms
ATG4D;autophagy-related 4D (yeast);cysteine protease ATG4D;9830134P12Rik;MGC31226;APG4 D;APG4D;ATG4 autophagy related 4 homolog D (S. cerevisiae);Atg4dl;AUT like 4 cysteine endopeptidase;AUTL4;Autophagin 4;Autophagy related cysteine endopeptidase 4;Autophagy related protein 4 homolog D;autophagin-4;AUT-like 4 cysteine endopeptidase;AUT-like 4, cysteine endopeptidase;autophagy-related protein 4 homolog D;APG4 (ATG4) autophagy-related homolog D;autophagy-related cysteine endopeptidase 4;cysteine protease involved in autophagy APG4-D;APG4-D
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATG4D-9977H | Recombinant Human ATG4D, His-tagged | E.coli | Human | His | 123-474a.a. | |
| ATG4D-2084M | Recombinant Mouse ATG4D Protein | Mammalian Cell | Mouse | His |
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| ATG4D-431H | Recombinant Human ATG4D protein, GST-tagged | Wheat Germ | Human | GST | 1 a.a. - 141 a.a. |
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| ATG4D-45HCL | Recombinant Human ATG4D lysate | HEK293 | Human | Non |
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| ATG4D-827M | Recombinant Mouse ATG4D Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ATG4D-827M-B | Recombinant Mouse ATG4D Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ATG4D involved in several pathways and played different roles in them. We selected most pathways ATG4D participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG4D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of autophagy | ATG3,IFNA12,IFNA3,INSB,PIK3C3,IFNA14,IFNA21,GABARAP,ULK3,GABARAPA |
Protein Function
ATG4D has several biochemical functions, for example, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG4D itself. We selected most functions ATG4D had, and list some proteins which have the same functions with ATG4D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase activity | CASP14,USP50,MALT1A,USP22,USP17L2,TINAG,CTSC,USP3,USP40,CASP8 |
Interacting Protein
ATG4D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG4D here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG4D.
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References
- Singh, KK; Yanagawa, B; et al. Autophagy gene fingerprint in human ischemia and reperfusion. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 147:1065-+(2014).
- Betin, VMS; Singleton, BK; et al. Autophagy facilitates organelle clearance during differentiation of human erythroblasts: Evidence for a role for ATG4 paralogs during autophagosome maturation. AUTOPHAGY 9:881-893(2013).
