ARL6IP5
-
Official Full Name
ADP-ribosylation factor-like 6 interacting protein 5 -
Overview
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. -
Synonyms
ARL6IP5;ADP-ribosylation factor-like 6 interacting protein 5;PRA1 family protein 3;addicsin;protein JWa;ARL-6-interacting protein 5;prenylated Rab acceptor protein 2;glutamate transporter EAAC1-interacting protein;ADP-ribosylation-like factor 6 in
Recombinant Proteins
- Human
- Mouse
- Chicken
- Cynomolgus
- Rhesus macaque
- Rat
- Mus musculus
- Macaca fascicularis
- Sus scrofa (Pig)
- Pongo Abelii
- Bovine
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- GST
- His
- His&SUMO
- Non
- His&Fc&Avi
Involved Pathway
ARL6IP5 involved in several pathways and played different roles in them. We selected most pathways ARL6IP5 participated on our site, such as Glutamate Neurotransmitter Release Cycle,Neuronal System,Neurotransmitter Release Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL6IP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutamate Neurotransmitter Release Cycle | RERG,RAB3AB,PPFIA4,GLS2B,SLC1A7B,PPFIA2,SNAP25A,CPLX2L,BZRAP1,SYT1A |
| Neurotransmitter Release Cycle | SLC1A3B,PPFIA1,SNAP25B,PPFIA2,UNC13B,LIN7C,SYN3,SYT1A,SLC6A1B,SYN1 |
| Transmission across Chemical Synapses | LIN7C,PICK1,GABRR2A,SLC1A3B,SLC17A7A,NCALDA,RERG,SLC1A2B,CPLX2L,SLC1A7A |
| Neuronal System | SLC1A3A,KCNH5A,Apba1,GLS2B,KCNK3A,KCNMB2,KCNK2B,KCND3,AKAP5,KCNJ1A.6 |
Protein Function
ARL6IP5 has several biochemical functions, for example, molecular_function,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL6IP5 itself. We selected most functions ARL6IP5 had, and list some proteins which have the same functions with ARL6IP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RGS2,MRPL20,GZMB,PCGF6,ZNF473,PGF,SREBF2,GOLGA2,RHOT2,EWSR1A |
| molecular_function | UBAP2B,LIPN,MORC2B,INPP4AA,FADS6,TARM1,SAMSN1B,TNNI2A.2,MEGF10,TMEM117 |
| protein C-terminus binding | CORO1A,NPAT,NEIL1,VTA1,DBNL,CITED1,PICK1,SIRT1,KCNJ11,OPRL1 |
Interacting Protein
ARL6IP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL6IP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL6IP5.
RNF185;PRAF2;CCR5;q7ard3_yerpe
Resources
Related Services
Related Products
References
- Wu, Y; Yang, M; et al. Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis. CELL DEATH & DISEASE 5:-(2014).
- Liu, X; Wang, SY; et al. Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer. PLOS ONE 7:-(2012).
