ARL13B
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Official Full Name
ADP-ribosylation factor-like 13B -
Overview
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants. -
Synonyms
ARL13B;ADP-ribosylation factor-like 13B;ADP ribosylation factor like 2 like 1 , ARL2L1;ADP-ribosylation factor-like protein 13B;DKFZp761H079;JBTS8;ADP ribosylation factor like 13B;ADP ribosylation factor like 2 like 1;ARL2L1;ARL2-like protein 1;ADP-ribosylation factor-like 2-like 1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARL13B-9851H | Recombinant Human ARL13B, GST-tagged | E.coli | Human | GST | 1-321a.a. | |
| ARL13B-1923M | Recombinant Mouse ARL13B Protein | Mammalian Cell | Mouse | His |
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| ARL13B-805H | Recombinant Human ARL13B protein, GST-tagged | Wheat Germ | Human | GST |
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| ARL13B-9543Z | Recombinant Zebrafish ARL13B | Mammalian Cell | Zebrafish | His |
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| ARL13B-8720HCL | Recombinant Human ARL13B 293 Cell Lysate | HEK293 | Human | Non |
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| ARL13B-8721HCL | Recombinant Human ARL13B 293 Cell Lysate | HEK293 | Human | Non |
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| Arl13b-1703M | Recombinant Mouse Arl13b Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ARL13B-2385H | Recombinant Human ARL13B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ARL13B-717M | Recombinant Mouse ARL13B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ARL13B-717M-B | Recombinant Mouse ARL13B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ARL13B involved in several pathways and played different roles in them. We selected most pathways ARL13B participated on our site, such as ARL13B-mediated ciliary trafficking of INPP5E,Assembly of the primary cilium,Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL13B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cargo trafficking to the periciliary membrane | EXOC3,BBS9,CNGA5,UNC119B,EXOC6,BBS10,EXOC1,MKKS,CCT4,BBS4 |
| Assembly of the primary cilium | WDR34,FGFR1OP,OST4,ARF4A,MKKS,PROL1,LZTFL1,DYNLL2A,CEP72,CCDC123 |
| Organelle biogenesis and maintenance | IFT27,CNGA2,MRPL48,DYNLL2B,UNC119B,MRPL40,DYNLRB1,BBS13,MRPS28,GFM2 |
Protein Function
ARL13B has several biochemical functions, for example, GTP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL13B itself. We selected most functions ARL13B had, and list some proteins which have the same functions with ARL13B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ANLN,WDYHV1,ARHGAP1,ACVR1,CTGF,GCH1,PDLIM3,EFCAB11,CALCOCO2,ARL6IP1 |
| GTP binding | RRAS,EIF2B1,IRGQ,SEPT12,REM1,ARL2,NKIRAS1,HSP90AB1,RAB11AL,EIF2S3Y |
Interacting Protein
ARL13B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL13B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL13B.
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