ARHGDIG

  • Official Full Name

    Rho GDP dissociation inhibitor (GDI) gamma
  • Overview

    The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).
  • Synonyms

    ARHGDIG;Rho GDP dissociation inhibitor (GDI) gamma;rho GDP-dissociation inhibitor 3;RhoGDI gamma;RHOGDI 3;GDIR3_HUMAN;OTTHUMP00000067353;OTTHUMP00000194914;Rho GDI 3;Rho GDI gamma;Rho GDP dissociation inhibitor 3;Rho GDP dissociation inhibitor gamma;Rho-GDI gamma;RHOGDI3;OTTHUMP00000067352;RHOGDI-3

Recombinant Proteins

  • Human
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • In Vitro Cell Free System
  • HEK293
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARHGDIG-9830H Recombinant Human ARHGDIG, His-tagged E.coli Human His 1-225a.a.
ARHGDIG-11376Z Recombinant Zebrafish ARHGDIG Mammalian Cell Zebrafish His
ARHGDIG-617H Recombinant Human ARHGDIG Mammalian Cell Human His
ARHGDIG-776H Recombinant Human ARHGDIG protein, GST-tagged Wheat Germ Human GST
ARHGDIG-115HCL Recombinant Human ARHGDIG cell lysate Human Non
ARHGDIG-1189HF Recombinant Full Length Human ARHGDIG Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 225 amino acids
ARHGDIG-2495H Recombinant Human ARHGDIG Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
ARHGDIG-2495H-B Recombinant Human ARHGDIG Protein Pre-coupled Magnetic Beads HEK293 Human
ARHGDIG-26234TH Recombinant Human ARHGDIG Wheat Germ Human Non 225 amino acids
ARHGDIG-26HF Recombinant Full Length Human ARHGDIG Protein In Vitro Cell Free System Human Full L. 225 amino acids

    Involved Pathway

    ARHGDIG involved in several pathways and played different roles in them. We selected most pathways ARHGDIG participated on our site, such as Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGDIG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neurotrophin signaling pathway CALML3,RPS6KA3,RIPK2,BAX,MAPK3,TP53,NGF,PRKCD,MAP2K5,MAP3K3

    Protein Function

    ARHGDIG has several biochemical functions, for example, GTPase activator activity,Rho GDP-dissociation inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGDIG itself. We selected most functions ARHGDIG had, and list some proteins which have the same functions with ARHGDIG. You can find most of the proteins on our site.

    Function Related Protein
    Rho GDP-dissociation inhibitor activity ARHGDIA,ARHGDIB
    GTPase activator activity TBC1D10A,ARHGAP18,RGS21,ASAP1,ALS2CL,TBC1D2,ARHGEF19,RIC8,SMAP2,GNAQ
    protein binding ACCS,ZNF785,RAC3,PATL1,ESRP1,MYO7A,LGI4,PDE9A,VPS36,BICD1

    Interacting Protein

    ARHGDIG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGDIG here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGDIG.

    CEP170P1;KXD1

    Resources

    References

    • Wang, J; Li, X; et al. Overexpression of Rho-GDP-Dissociation Inhibitor-gamma Inhibits Migration of Neural Stem Cells. JOURNAL OF NEUROSCIENCE RESEARCH 91:1394-1401(2013).
    • Wang, J; Cheng, H; et al. Regulation of Neural Stem Cell Differentiation by Transcription Factors HNF4-1 and MAZ-1. MOLECULAR NEUROBIOLOGY 47:228-240(2013).

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