ARFRP1
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Official Full Name
ADP-ribosylation factor related protein 1 -
Overview
The protein encoded by this gene is a membrane-associated GTP-ase and localizes to the plasma membrane. It is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. The gene is located in a gene cluster that includes the a gene (M68) that is overexpressed in some tumors. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
ARFRP1;ADP-ribosylation factor related protein 1;ADP-ribosylation factor-related protein 1;ARL18;ARP;Arp1;ADP ribosylation factor related protein 1;ARF related protein 1;ARF related protein;ARL 18;ARP 1;Helicase like protein NHL;MGC6837;SCG10 like protein;SCG10 like-protein;ARF-related protein 1;helicase-like protein NHL
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ARFRP1 involved in several pathways and played different roles in them. We selected most pathways ARFRP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARFRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ARFRP1 has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARFRP1 itself. We selected most functions ARFRP1 had, and list some proteins which have the same functions with ARFRP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ARL16,UBE2U,TRIM42,NR0B2,UBE2D1,TEKT3,PPP3CA,NOS1AP,YWHAH,RFC2 |
| GTPase activity | TUBA8L,RRAGC,GBP4,DNAJC27,RAB9B,RAC1,RAB28,RAB5C,RHOG,RAB24 |
| GTP binding | NOLC1,SEPHS1,IRGQ2,EEF1A1,TUBA7L,GTPBP4,GNA11B,NPR1,SUCLG1,RND1L |
Interacting Protein
ARFRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARFRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARFRP1.
pi3p
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References
- Shen, XY; Meza-Carmen, V; et al. Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:18788-18793(2008).
- Padilla, PI; Chang, MJ; et al. Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): Effects of FK506. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100:2322-2327(2003).
