APOO
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Official Full Name
apolipoprotein O -
Overview
This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16. -
Synonyms
APOO;apolipoprotein O;FAM121B, family with sequence similarity 121B;MGC4825;My025;brain my025;family with sequence similarity 121B;FAM121B
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mus musculus
- Bovine
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- His
- GST
- His&T7
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
APOO involved in several pathways and played different roles in them. We selected most pathways APOO participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APOO has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOO itself. We selected most functions APOO had, and list some proteins which have the same functions with APOO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | USP12,KRT5,PYGO2,RALGDS,SART3,GGA2,EFTUD2,FAM9A,IRX1,SIGLEC6 |
Interacting Protein
APOO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOO here. Most of them are supplied by our site. Hope this information will be useful for your research of APOO.
TIMMDC1
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References
- Viola, KL; Klein, WL; et al. Amyloid beta oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis. ACTA NEUROPATHOLOGICA 129:183-206(2015).
- Geetha, M; Kalaivani, V; et al. Plasma anti-alpha-galactoside antibody binds to serine- and threonine-rich peptide sequence of apo(a) subunit in Lp(a). GLYCOCONJUGATE JOURNAL 31:289-298(2014).
