APOBR
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Official Full Name
apolipoprotein B receptor -
Overview
Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. -
Synonyms
APOBR;apolipoprotein B receptor;APOB48R;APOB100R
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APOBR-9751H | Recombinant Human APOBR, GST-tagged | E.coli | Human | GST | C-term-238a.a. | |
| APOB48R-694H | Recombinant Human APOB48R protein, GST-tagged | Wheat Germ | Human | GST |
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| APOBR-744H | Recombinant Human APOBR | Mammalian Cell | Human | His |
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| APOBR-2486H | Recombinant Human APOBR Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| APOBR-2486H-B | Recombinant Human APOBR Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
APOBR involved in several pathways and played different roles in them. We selected most pathways APOBR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APOBR has several biochemical functions, for example, very-low-density lipoprotein particle receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBR itself. We selected most functions APOBR had, and list some proteins which have the same functions with APOBR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| very-low-density lipoprotein particle receptor activity | LDLR,VLDLR |
Interacting Protein
APOBR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBR here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBR.
q7ard3_yerpe;q81ye8_bacan
Resources
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References
- Dragan, S; Serban, MC; et al. Proprotein Convertase Subtilisin/Kexin 9 Inhibitors: An Emerging Lipid-Lowering Therapy?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS 20:157-168(2015).
- Tavori, H; Rashid, S; et al. On the function and homeostasis of PCSK9: Reciprocal interaction with LDLR and additional lipid effects. ATHEROSCLEROSIS 238:264-270(2015).
