APOBEC3G
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Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -
Synonyms
APOBEC3G;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G;DNA dC->dU-editing enzyme APOBEC-3G;bK150C2.7;CEM15;dJ494G10.1;FLJ12740;MDS019;APOBEC-related protein 9;dU editing enzyme;ph
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- Mammalian cells
- in vitro E.coli expression system
- Non
- His
- GST
- His&Fc&Avi
- Myc&DDK
- Flag
- N-His-SUMO
Involved Pathway
APOBEC3G involved in several pathways and played different roles in them. We selected most pathways APOBEC3G participated on our site, such as APOBEC3G mediated resistance to HIV-1 infection,Disease,HIV Infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBEC3G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HIV Infection | NMT2,ELL,CHMP4B,DOCK2,SSRP1,RCC1,AP1S1,PACS1,AP1B1,VPS37A |
| Disease | NA,KREMEN2,LTF,AP1G1,CCDC167,HDAC6,CCR5,TAF1L,CHMP4C,CDK9 |
| Host Interactions of HIV factors | AP1G1,DOCK2,PPIAL4A,AP1S1,PSIP1,RCC1,AP1B1,AP1M2,PACS1 |
| Integrated Breast Cancer Pathway | DAG1,EDAR,JAKMIP1,LGALS13,MYT1,USP16,SMARCA4,USP15,NAB1,UBE2F |
| APOBEC3G mediated resistance to HIV-1 infection | BANF1,HMGA1,PSIP1,PPIA,gag |
| Infectious disease | STX1B,RCC1,CHMP4C,NMT1,VPS37A,ANTXR1,TAF1L,KPNA3,IPO5,PDCD6IP |
Protein Function
APOBEC3G has several biochemical functions, for example, RNA binding,cytidine deaminase activity,deoxycytidine deaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBEC3G itself. We selected most functions APOBEC3G had, and list some proteins which have the same functions with APOBEC3G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRIM35-23,S100A5,LMX1B,TRIM27,CBLL1,MMP7,SUV39H2,ADAM8A,RNF220A,L3MBTL1 |
| deoxycytidine deaminase activity | APOBEC3B |
| cytidine deaminase activity | APOBEC3F,CDA,WBP2NL,AICDA,APOBEC3H,APOBEC2,APOBEC1 |
| RNA binding | PSMA6,IFIT3,CSDC2,FAM120A,QKI2,ZNF74,SAMHD1,KHDC3L,SRSF1A,DDX59 |
| protein homodimerization activity | GJC3,HAND1,PRMT8,RCHY1,LHPP,KIAA0947,CARS,SYT6,SMAGP,SYNE1 |
| protein binding | MYO15,PARP9,TRAF3IP3,CAMTA2,TRIAP1,STAC,GSTM5,DST,COG3,CD2 |
Interacting Protein
APOBEC3G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBEC3G here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBEC3G.
gag;vif;PTN
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References
- D'arc, M; Ayouba, A; et al. Origin of the HIV-1 group O epidemic in western lowland gorillas. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E1343-E1352(2015).
- Lewis, DJM; Wang, YF; et al. Effect of Vaginal Immunization with HIVgp140 and HSP70 on HIV-1 Replication and Innate and T Cell Adaptive Immunity in Women. JOURNAL OF VIROLOGY 88:11648-11657(2014).
