APOBEC3B
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Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -
Overview
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A commonly-found deletion polymorphism of approximately 29.5 kb removes the 3 UTR of the adjacent APOBEC3A gene and the coding region of this gene and creates a hybrid of the two genes. -
Synonyms
APOBEC3B;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B;probable DNA dC->dU-editing enzyme APOBEC-3B;FLJ21201;phorbolin 3;PHRBNL;phorbolin 2;phorbolin-2/3;cytidine deaminase
Recombinant Proteins
- Rhesus macaque
- Human
- Mammalian Cell
- Wheat Germ
- Human cells
- E.coli
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- Flag
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APOBEC3B-361R | Recombinant Rhesus monkey APOBEC3B Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| APOBEC3B-697H | Recombinant Human APOBEC3B protein, GST-tagged | Wheat Germ | Human | GST |
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| APOBEC3B-94HCL | Recombinant Human APOBEC3B cell lysate | Human | Non |
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| APOBEC3B-01H | Recombinant Human APOBEC3B protein, DYKDDDDK-tagged | Human cells | Human | Flag |
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| APOBEC3B-0207H | Recombinant Human APOBEC3B Protein (Met1-Arg190), N-His-tagged | E.coli | Human | His | Met1-Arg190 |
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| APOBEC3B-1143HF | Recombinant Full Length Human APOBEC3B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 251 amino acids |
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| APOBEC3B-146H | Recombinant Human APOBEC3B Protein, His tagged | E.coli | Human | His |
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| APOBEC3B-190R | Recombinant Rhesus Macaque APOBEC3B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| APOBEC3B-190R-B | Recombinant Rhesus Macaque APOBEC3B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
APOBEC3B involved in several pathways and played different roles in them. We selected most pathways APOBEC3B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBEC3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
APOBEC3B has several biochemical functions, for example, deoxycytidine deaminase activity,poly(A) RNA binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBEC3B itself. We selected most functions APOBEC3B had, and list some proteins which have the same functions with APOBEC3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRIM48,MARCH9,ADAM8A,Npepo,RNF144AA,RNF38,PAM,CIZ1,NR2F1,NEURL1AB |
| poly(A) RNA binding | YWHAE,CNBP,SRFBP1,DDX41,SCAF4,CCBL2,NOVA2,RPL5A,GTL3,EIF2S1A |
| deoxycytidine deaminase activity | APOBEC3G |
Interacting Protein
APOBEC3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBEC3B here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBEC3B.
HNRNPA1;PPP1CC;MATR3;HNRNPH2;Fus;PPP1CB;Snrnp70;Srsf1;Taf15;MAP1LC3C;GABARAPL1;GABARAPL1;MAP1LC3A;BCLAF1;Dctn3;Shcbp1
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