APLNR
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Official Full Name
APLNR apelin receptor -
Synonyms
APLNR;apelin receptor;AGTRL1, angiotensin II receptor like 1;APJ;APJ (apelin) receptor;APJR;FLJ90771;APJ receptor;HG11 orphan receptor;angiotensin receptor-like 1;G protein-coupled receptor APJ;G-protein coupled receptor APJ;angiotensin II receptor-like 1;G-protein coupled receptor HG11;HG11;AGTRL1;FLJ96609;MGC45246
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Mus musculus
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Macaca mulatta
- E.coli
- E.Coli or Yeast
- Mammalian Cell
- Wheat Germ
- HEK293
- Insect Cell
- In Vitro Cell Free System
- Mammalian cells
- HEK293T
- E.coli expression system
- GST
- His
- Non
- His&Myc
- His&Flag
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
APLNR involved in several pathways and played different roles in them. We selected most pathways APLNR participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with APLNR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCR ligand binding | ACKR4,SETD6,OXER1,SST1.1,CCR1,EMR3,OXTRL,CHRM4,OXGR1,EDN1 |
| Signal Transduction | INTU,PYGO1,S1PR3,AKR1C6,TLE2,PTHLH,ARHGAP10,GDI1,PDK3B,BOC |
| GPCRs, Class A Rhodopsin-like | DRD4,PTGDR2,CCR1,GPR1,OPN3,ADORA1,GPR85,GPR12,GPR171,HRH3 |
| GPCR downstream signaling | TAC1,FPR-RS3,NTS,DRD5,ANXA1,GCGA,S1PR5B,PYY,OPN1SW,DGKB |
| Neuroactive ligand-receptor interaction | GRIN1,S1PR4,OPRL1,GABRG2,NPFFR2,BRS3,TAAR14L,ADRA2DA,DRD1A,GRIK1 |
| Class A/1 (Rhodopsin-like receptors) | CHRM4,CCL35.2,CCR8,NMBB,PYYA,SSTR4,PYY,EDNRA,RLN2,POMCB |
| G alpha (i) signalling events | CXCR7B,SSTR3,NPB,LPAR2A,CCR3,OXER1,TAS2R13,GPR55,CHRM4,DRD2 |
| Peptide ligand-binding receptors | SSTR4,SSTR1,KISS1,GAL,RLN3A,NMBA,CCRL2,EDN3,QRFP,CCK |
Protein Function
APLNR has several biochemical functions, for example, G-protein coupled receptor activity,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APLNR itself. We selected most functions APLNR had, and list some proteins which have the same functions with APLNR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | VMN1R49,TLR6,TLR2,JMJD6,NOTCH4,CADM2,LDLR,SV2A,EPHB6,ATP6AP2 |
| G-protein coupled receptor activity | OLFCH1,OXTRL,OR3A2,OPN4XB,OLFR481,TAAR14A,FZD8,OLFCG5,LPAR2A,NPY8BR |
Interacting Protein
APLNR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APLNR here. Most of them are supplied by our site. Hope this information will be useful for your research of APLNR.
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Resources
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References
- Yasuzaki, H; Yoshida, S; et al. Involvement of the apelin receptor APJ in Fas-induced liver injury. LIVER INTERNATIONAL 33:118-126(2013).
