ANXA3
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Official Full Name
annexin A3 -
Overview
This gene encodes a member of the annexin family.Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways.This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. -
Synonyms
ANXA3;annexin A3;1 2 cyclic inositol phosphate phosphodiesterase;2-cyclic phosphate 2-phosphohydrolase;35 alpha calcimedin;35-alpha calcimedin;Annexin III;Annexin-3;AnnexinA3;AnnexinIII;ANX 3;ANX A3;ANX3;ANXA 3;ANXA3_HUMAN;Calcimedin 35 alpha;Inositol 1 2 cyclic phosphate 2 phosphohydrolase;Inositol 1;Lipocortin III;LipocortinIII;OTTHUMP00000160701;OTTHUMP00000219237;OTTHUMP00000219238;PAP III;PAP-III;PAPIII;Placental anticoagulant protein III;calcimedin 35-alpha;Annexin III (lipocortin III);inositol 1,2-cyclic phosphate 2-phosphohydrolase
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E.Coli or Yeast
- Wheat Germ
- In Vitro Cell Free System
- Mammalian cells
- Yeast
- HEK293T
- GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
ANXA3 involved in several pathways and played different roles in them. We selected most pathways ANXA3 participated on our site, such as Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prostaglandin Synthesis and Regulation | ANXA4,CC10,S100A10,S100A6,ANXA6,ANXA5,ANXA2 |
Protein Function
ANXA3 has several biochemical functions, for example, calcium ion binding,calcium-dependent phospholipid binding,calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA3 itself. We selected most functions ANXA3 had, and list some proteins which have the same functions with ANXA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phospholipase A2 inhibitor activity | ANXA2,ANXA1,CC10 |
| calcium-dependent phospholipid binding | SYT11A,ANXA5,SYT11,SYTL2,SYT17,ANXA11A,ANXA2A,SYT5A,PLA2G4B,SYT7B |
| calcium-dependent protein binding | MYO5A,MMP13,FCN2,PDCD6,KCNIP3,TNNT3,CHP,NRXN1,TSG101,STMN2 |
| calcium ion binding | PADI4,PCDHB12,EFCAB4A,F9,BGLAP-RS1,CALM3,PCDH2G8,SYTL2,MMP20,ANXA6 |
Interacting Protein
ANXA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA3.
TP53;UNC119;UBR1;EMG1;IGSF21;pi3p;ATF2
Resources
Research Area
Cancer Drug TargetsOther Coagulation Cascade Molecules
Fertilization Molecules
Chondrogenesis Markers
Related Services
Related Products
References
- Hamelin-Peyron, C; Vlaeminck-Guillem, V; et al. Prostate cancer biomarker annexin A3 detected in urines obtained following digital rectal examination presents antigenic variability. CLINICAL BIOCHEMISTRY 47:901-908(2014).
- Suzuki, T; Ikari, K; et al. PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study. PLOS ONE 8:-(2013).
