ALOX15
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Official Full Name
arachidonate 15-lipoxygenase -
Overview
Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene. -
Synonyms
ALOX15;arachidonate 15-lipoxygenase;15 LOX 1;15-LOX;15-lipooxygenase-1;arachidonate omega-6 lipoxygenase;15LOX-1;15-LOX-1
Recombinant Proteins
- Human
- Rat
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- Insect cells
- In Vitro Cell Free System
- His
- GST
- Non
- FLAG
- His&Fc&Avi
- Avi&His&Fc
- Myc&DDK
- Flag
Involved Pathway
ALOX15 involved in several pathways and played different roles in them. We selected most pathways ALOX15 participated on our site, such as Arachidonic acid metabolism,Linoleic acid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALOX15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Serotonergic synapse | HTR1F,MAPK3,CYP2C54,HTR3E,PLA2G4D,PTGS1,MAOB,GNGT1,GNB1,ALOX12E |
| Metabolic pathways | UMPS,ADPGK,GFPT1,HIBCH,PFKMB,POLD4,DHDPSL,GLULC,CES1,CES1C |
| Linoleic acid metabolism | CYP2C70,PLA2G4C,CYP2C45,PLA2G4AA,CYP2C19,CYP2C54,CYP3A25,PLA2G5,CYP3A65,PLA2G1B |
| Arachidonic acid metabolism | CYP1A2,PTGES3,PLA2G4B,AKR1C3,CYP2C9,GGT1,CYP2B6,CYP2AD6,LTC4S,ALOX12 |
Protein Function
ALOX15 has several biochemical functions, for example, arachidonate 12-lipoxygenase activity,arachidonate 15-lipoxygenase activity,eoxin A4 synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALOX15 itself. We selected most functions ALOX15 had, and list some proteins which have the same functions with ALOX15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| arachidonate 12-lipoxygenase activity | ALOX12E,ALOX12B,ALOX12 |
| iron ion binding | SC4MOL,MTRR,CYP46A1.4,HBM,CH25HL2,P4HA1A,CYP19A1B,CYP2AA9,HIF1AN,TMLHE |
| arachidonate 15-lipoxygenase activity | ALOX15B,ALOX8 |
| protein binding | BCAM,KRT80,LNPEP,UNC13A,ACTN2,JUN,GSK3B,PTPN23,CD93,SOCS4 |
| hepoxilin-epoxide hydrolase activity | ALOX12 |
| phosphatidylinositol-4,5-bisphosphate binding | FRMPD4,COMMD1,SNX18,SYTL2,PHLDA3,FAM21C,SNX21,KRIT1,SNX20,STXBP6L |
| hepoxilin A3 synthase activity | ALOX12 |
Interacting Protein
ALOX15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALOX15 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALOX15.
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