AKR1B10

  • Official Full Name

    aldo-keto reductase family 1, member B10 (aldose reductase)

  • Overview

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]

  • Synonyms

    AKR1B10;aldo-keto reductase family 1, member B10 (aldose reductase);HIS;HSI;ARL1;ARL-1;ALDRLn;AKR1B11;AKR1B12;aldo-keto reductase family 1 member B10;ARP;hARP;SI reductase;aldose reductase-like 1;small intestine reductase;aldose reductase-like peptide;aldose reductase-related protein;aldo-keto reductase family 1, member B11 (aldose reductase-like)

Recombinant Proteins

  • Human
  • Chicken
  • E.coli
  • Sf21 Insect Cell
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • Non
  • His
  • GST
  • His&T7
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1B10-406H Active Recombinant Human AKR1B10 protein E.coli Human Non 1-316 a.a.
AKR1B10-995H Active Recombinant Human AKR1B10 Protein, Met & His-tagged Sf21 Insect Cell Human His Ala2-Tyr316
AKR1B10-27154TH Recombinant Human AKR1B10 E.coli Human Non 316 amino acids
AKR1B10-27155TH Recombinant Human AKR1B10 E.coli Human Non Full L. 1-316 a.a.
AKR1B10-2764H Recombinant Human AKR1B10, His-tagged E.coli Human His
AKR1B10-410H Recombinant Human AKR1B10 Protein, GST-tagged Wheat Germ Human GST
AKR1B10-6197C Recombinant Chicken AKR1B10 Mammalian Cell Chicken His
AKR1B10-8931HCL Recombinant Human AKR1B10 293 Cell Lysate HEK293 Human Non
AKR1B10-0093H Recombinant Human AKR1B10 Protein (Met1-Tyr316), N-His-tagged E.coli Human His Met1-Tyr316
AKR1B10-0254H Recombinant Human AKR1B10 Protein (M1-Y316), Tag Free E.coli Human Non M1-Y316
AKR1B10-0255H Recombinant Human AKR1B10 Protein (M1-Y316), His tagged E.coli Human His M1-Y316
AKR1B10-1365HF Recombinant Full Length Human AKR1B10 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 316 amino acids
AKR1B10-1533H Recombinant Human AKR1B10 protein, His & T7-tagged E.coli Human His&T7 Met1~Tyr316
AKR1B10-301110H Recombinant Human AKR1B10 protein, GST-tagged E.coli Human GST Met1-Tyr316

    Involved Pathway

    AKR1B10 involved in several pathways and played different roles in them. We selected most pathways AKR1B10 participated on our site, such as Pentose and glucuronate interconversions,Fructose and mannose metabolism,Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKR1B10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pentose and glucuronate interconversions UGT1A6A,ALDH3A2,DCXR,AKR1B7,UGT1A3,UGT2A2,UGT1A4,ALDH2.2,AKR1B1,UGT1A2
    Galactose metabolism Akr1b3,HK1,GALE,B4GALT1,AKR1B8,AKR1B1,UGP2,PFKL,GALK1,LALBA
    Glycerolipid metabolism ALDH2.1,MBOAT2B,AKR1A1A,PPAP2A,MGLL,DAK,GLYCTK,LPL,AGPAT9L,TAE1
    Fructose and mannose metabolism PFKMB,PMM1,FBP1A,PFKP,PFKFB2,TSTA3,ALDOAB,GMDS,Akr1b3,C12orf5
    Metabolic pathways PAH,NAT,NDUFA13,PGD,NT5C1B-RDH14,ALOX12,LDHC,GMPPB,CYP19A1,NDUFB5

    Protein Function

    AKR1B10 has several biochemical functions, for example, aldo-keto reductase (NADP) activity,geranylgeranyl reductase activity,indanol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AKR1B10 itself. We selected most functions AKR1B10 had, and list some proteins which have the same functions with AKR1B10. You can find most of the proteins on our site.

    Function Related Protein
    retinal dehydrogenase activity ALDH8A1,Aldh1a7,AKR1B8,ALDH1A1,AKR1C6,AKR1C3,ALDH1A3,AKR1C4
    geranylgeranyl reductase activity AKR1C3,AKR1B8
    protein binding NHP2,S100A9,MED23,CCDC92,CSGALNACT2,GABPB1,ENTPD1,GIT1,NUAK2,IPO13
    aldo-keto reductase (NADP) activity H2-KE6,MIOX,AKR1C4,SDR42E1,AKR1C21,AKR1B1,KCNAB2,AKR1C6,KCNAB1,HSD3B6
    indanol dehydrogenase activity AKR1B8,AKR1C3

    Interacting Protein

    AKR1B10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKR1B10 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKR1B10.

    ACACA;TERF2IP;Nedd1;Jup;Slain1;TSNAX

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