AEBP1
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Official Full Name
AE binding protein 1 -
Overview
The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells. -
Synonyms
AEBP1;AE binding protein 1;adipocyte enhancer-binding protein 1;ACLP;adipocyte enhancer binding protein 1;aortic carboxypeptidase like protein;AE-binding protein 1;aortic carboxypeptidase-like protein;FLJ33612
Recombinant Proteins
- Mouse
- Rat
- Human
- S.cerevisiae
- E.coli
- E.Coli or Yeast
- Wheat Germ
- Mammalian Cell
- HEK293
- S.cerevisiae
- His&SUMO
- His
- GST
- His&Fc&Avi
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AEBP1-1393M | Recombinant Mouse Aebp1 protein, His/sumo-tagged | E.coli | Mouse | His&SUMO |
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| Aebp1-3196R | Recombinant Rat Aebp1, His-tagged | E.Coli or Yeast | Rat | His | 1128 |
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| AEBP1-394H | Recombinant Human AEBP2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| AEBP1-550R | Recombinant Rat AEBP1 Protein | Mammalian Cell | Rat | His |
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| AEBP1-206R | Recombinant Rat AEBP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| AEBP1-206R-B | Recombinant Rat AEBP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Aebp1-4526M | Recombinant Mouse Aebp1 protein, His-SUMO-tagged | E.coli | Mouse | His&SUMO | 26-370aa |
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| AEBP1-8321S | Native S. cerevisiae AEBP1 | S.cerevisiae | S.cerevisiae | Non |
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Involved Pathway
AEBP1 involved in several pathways and played different roles in them. We selected most pathways AEBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AEBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AEBP1 has several biochemical functions, for example, DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AEBP1 itself. We selected most functions AEBP1 had, and list some proteins which have the same functions with AEBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metallocarboxypeptidase activity | CPA3,CPA4,FOLH1,CPA6,CPM,CPD,CPB1,CPA5,AGBL3,CPO |
| DNA binding | SUPV3L1,PIF1,NKX3-1,RAD51L1,VEZF1,ABT1,NR2F1B,FANCI,MEF2C,ZFP326 |
| transcription corepressor activity | RARA,SOD3,TLE4,C1QBP,SKI,NCOR2,NEUROD2,ALX1,HDAC4,DDX54 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | ETV7,ESX1,ZC3H8,ZBTB12.2,ETV6,DMBX1,BCL6AB,ARHGAP35,MSX2,ETV3 |
| calmodulin binding | RYR2,CNN1A,NRGN,NOS3,MARCKS,MYH1,MYO10,GRIN1,ITPKB,MKNK2A |
| RNA polymerase II regulatory region sequence-specific DNA binding | DLX2,KAT2B,FOXK1,NR1D1,CDX1B,ATF3,ATF4,PRKCBP1L,BHLHA15,HMX3 |
| carboxypeptidase activity | PGCP,NAALAD2,ACE2,AGBL1,BLMH,CTSA,CPB1,CNDP1,CNDP2,AGBL4 |
| zinc ion binding | TRIM48,RUNX1,RASGRP1,G2E3,PTGR1,GFI1,RXRG,S100A9,PHF10,LHX2 |
Interacting Protein
AEBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AEBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AEBP1.
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